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清开灵注射液对实验性脑出血大鼠脑内P物质的影响 被引量:21

Effect of Qingkailing Injection on the Content of Substance P in the Brain of Cerebral Hemorrhagic Rat
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摘要 采用胶原酶注入脑内造膜法,经ABC免疫组织化学技术显示了清开灵注射液对脑出血大鼠脑内P物质(SP)的分布及含量影响。揭示清开灵注射液治疗脑中风的机理之一很可能是通过调节脑内SP的含量达到治病疗效的。 Collagenase was injected into the caud putamen nucleus of rat ic induce intracerebral hemorrhage. Then, immunohistochemical technique was used to determine the effect of Qingkailing injection on the content of substance P (SP) in the brain of cerebral hemorrhagic rat. The results of the present study imply that one of the mechanisms of Qingkailing injection treatment of strode is involved in the change of SP content.
机构地区 北京中医药大学
出处 《北京中医药大学学报》 CAS CSCD 1996年第6期67-69,共3页 Journal of Beijing University of Traditional Chinese Medicine
基金 国家八五攻关课题
关键词 清开灵注射液 脑出血 P物质 Qingkailing Injection Cerebral Hemorrhagic Model SP Rat Immunohistochemistry
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  • 1Dr. J. M. Lundberg,A. ?ngg?rd,J. Pernow,T. H?kfelt. Neuropeptide Y-, substance P- and VIP-immunoreactive nerves in cat spleen in relation to autonomic vascular and volume control[J] 1985,Cell and Tissue Research(1):9~18
  • 2John Foreman,Chris Jordan. Histamine release and vascular changes induced by neuropeptides[J] 1983,Agents and Actions(2-3):105~116

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