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溃疡性结肠炎患者血浆白介素-1β的变化 被引量:4

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摘要 目的为观察溃疡性结肠炎患者血浆白介素-1β变化,了解其在发病中的作用。方法采用ELISA法检测44例不同程度的溃疡性结肠炎患者,14例肠易激综合征患者和14例正常对照者血浆白介素-1β的含量。结果重度溃疡性结肠炎血浆白介素-1β的含量与肠易激综合症组和正常对照组比较差异均有显著意义(P<0.05),而肠易激综合征组和正常对照组之间无显著差异。结论血浆白介素-1β参与溃疡性结肠炎的发病,检测血浆白介素-1β对研究溃疡性结肠炎的发病机制和判断溃疡性结肠炎的病情具有一定的参考价值。
作者 万德惠 徐萍
出处 《江西医药》 CAS 2006年第7期485-486,共2页 Jiangxi Medical Journal
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参考文献5

  • 1潘国宗 曹世植.现代胃肠病学(第1版)[M].北京:科学出版社,1994.1245-1259.
  • 2欧阳钦,潘国宗,温忠慧,万学红,胡仁伟,林三仁,胡品津.对炎症性肠病诊断治疗规范的建议[J].中华消化杂志,2001,21(4):236-239. 被引量:1125
  • 3H Reinecrer,M Steffen,T Witthdeft,et al.Ehanced secretion of tumour necrosis factor-alpha,IL-6,and IL-1β by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn s disease.Clin Exp Immunol,1993,94:174
  • 4MZ Mazlarn,HJF Hodgson.Interrelations between interleukin-6,interleukin-1β,plasma C-reactive protein values,and in vitro C-reactive protein generation in patients with inflammatory bowel disease.Gut,1994,35:77
  • 5张文俊,许国铭,李兆申,龚燕芳,屠振兴,许爱芳.血清白细胞介素1β与溃疡性结肠炎的关系[J].第二军医大学学报,2002,23(12):1345-1347. 被引量:8

二级参考文献13

  • 1褚行琦.炎症性肠病的内镜检查[A].郑家驹.炎症性肠病[C].上海:上海科学技术文献出版社,1998.103—108.
  • 2Das KM,Dasgupta A,Geng X. Autoimmunity to cytoskeletal protein tropomysin: a clue to the pathogenetic mechanism for ulcerative colitis[J]. J Immunol, 1993,150(6): 2487-2493.
  • 3Biancone L,Mandal A,Yang H,et al. Production of immunogobulin G and G1 antibodies to cytoskeletal protein by lamina propria cells in ulcerative colitis [J]. Gastroenterology, 1995,109(1) :3-12.
  • 4Yang F,de Villiers WJ,Lee EY,et al. Increased nuclear factorkappaB activation in colitis of interleukin-2-deficient mice[J]. J Lab Clin Med,1999,134(4):378-385.
  • 5Neurath MF,Fuss I,Schurmann G,et al. Cytokine gene transcription by NF-kappa B family members in patients with inflammatory bowel disease[J]. Ann N Y Acad Sci, 1998,859(1):149-159.
  • 6Nemetz A,Kope A,Molnar T,et al. Significant differences in the interleukin-1beta and interleukin-1 receptor antagonist gene polymorphisms in a Hungarian population with inflammatory bowel disease [J]. Scand J Gastroenterol, 1999, 34 (2):175-179.
  • 7Diag R, Rogler G, Aschenbrenner E, et al. Human intestinal cells secrete interlukin-1 receptor antagonist and interlukin-8 but not interleukin-1 or interleukin-6 [J]. Gut, 2000,46 (3):350-358.
  • 8Evgenikos N, Bartolo DC, Hamer-Hodges DW, et al. Assessment of ileoanal pouch inflammation by interleukin 1beta and interleukin 8 concentrations in the gut lumen [J]. Dis Colon Rectum, 2002,45 (2): 249-255.
  • 9Bitton A,Peppercorn MA,Antonioli DA,et al. Clinical ,biological, and histologic parameters of relapse in ulcerative colitis [J]. Gastroenterology,2001,120(1): 13-20.
  • 10Nielsen OH, Vainer B, Madsen SM,et al. Established and emerging biological activity markers of inflammatory bowel disease[J]. AmJ Gastroenterol,2000,95(2):359-367.

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