摘要
目的探讨儿童个人过敏原与荨麻疹发病之间的关系。方法采用酶免疫分析法检测114例儿童荨麻疹患者和12名健康对照者血清食入性和吸入性过敏原特异性的IgE。结果114例儿童荨麻疹患者过敏原总阳性率为73.7%,明显高于健康对照17.7%的阳性率(P<0.01);28.1%(32/114)患儿食入性和吸入性过敏原同时检出阳性;57.9%(66/114)的患儿检出阳性2种或2种以上。食入性过敏原中对螃蟹、虾、龙虾最敏感,且随着年龄的增长阳性率逐渐降低;吸入性过敏原中尘(粉)螨阳性率最高,且随年龄的增加逐渐增高。结论儿童个人过敏原与部分荨麻疹的发生发展有密切的关系,不同年龄段过敏原构成不同,螃蟹、虾、龙虾和尘(粉)螨是广州地区儿童荨麻疹的常见病因之一。
Objective To explore the relationship between the exposure of children to individual allergens and occurrence of urticaria. Methods The specific IgE of food and inhalant allergens were serologieally determined by EIA in the sera of 114 urticaria children and 12 healthy controls. Results Out of 114 eases of children urticaria children examined, the total positive rate was 73. 7% and 17.7% in control group, showing significant difference between two groups （ P 〈0.01）. Food and inhalant allergens were simultaneously detected from 28.1% （32/114） patients. Two or more than two allergens were deteeted from 57.9 % （66/114） patients, crab,shrimp and lobster were the main food allergens and the positive rate was gradually increased along with the increasing age of the patients. The positive rate in the those exposed to Dermatophagoides was the highest and it was increases along with the increasing age of the patients. Conclusion The exposure of ehioldren to individual allergens is nssoeiated with the occurrence of urticaria in children. The exposure of children to erab,shrimp,lobster and Dermatophagoides are one of the important eanse for the oecurrence of urticaria in children in Guangzhou.
出处
《中国热带医学》
CAS
2006年第8期1438-1439,共2页
China Tropical Medicine
关键词
过敏原
荨麻疹
儿童
Allergen
Urticaria
Children
