摘要
目的 探讨影响胰头癌根治性切除术后并发症的相关因素。方法 回顾性分析1999年1月～2005年7月我院行Whipple或保留幽门Whipple手术的44例胰头癌病例，对患者的11项临床观察指标与术后并发症及病死率进行因素分析。结果 本组术后并发症发生率为29．55％，病死率为2．27％。术前有低蛋白血症、糖尿病史、手术时间超过4小时、术后无肠内营养、术中出血大于1000ml者，胰肠行端端吻合者，由非专业医师实施手术者，术后并发症及病死率明显升高（P〈0．01）。术后出现并发症及死亡病例者与无并发症者之间的术前APACHEⅡ评分存在显著性差异（P〈0．01）。结论 胰头癌根治性切除风险大，并发症多且病死率高，必须加强术前充分评估和围手术期处理。
Objective To explore complication of post radical excision in patients with cancer of pancreatic head. Methods The clinical data of 44 patients with cancer of pancreatic head undergoing pylorus-preserving pancreaticoduodenectomy or Whipple operation from 1999,01 to 2005,07,them were studied the relationship between 11 signs found at postoperative complications and fatality rate was multivarities analyzed. Results The postoperative complication rate was 29.55% ,the fatality rate was 2. 27%. Both were in a significant correlation with hypoproteinemia, diabetes, intraoperative estimated blood loss（ 〉 1000 ml）, operative time （ 〉 4 hours）, no enteral nutrition postoperation, end - to - end anastomosis for entero - pancreas, and practiced by of non-speciality surgeons （ P 〈 0. 01 ）. It has a significant difference in the scores of APACHE II between postoperative complication and no postoperative complication in patients（P 〈 0. 01 ）. Conclusion It is a high risk for radical excision in patients with cancer of pancreatic head. postoperative complications and fatality rate were higer,and sufficient evaluation and treatment of surround operation were important, morbidity.
出处
《肝胆外科杂志》
2006年第3期186-188,共3页
Journal of Hepatobiliary Surgery
关键词
胰头癌
根治性切除
并发症
cancer of pancreatic head
radical excision
complication
