摘要
目的 分析减轻黄疸 (以下简称减黄 )、介入化疗和手术切除“3阶段法”治疗大胰头癌的效果。方法 收集本院近 1年收治的 16例大胰头癌 (大于 6cm)患者 (均伴有黄疸 ) ,采用上述“3阶段法”治疗。先行胆囊造瘘以缓解黄疸 ,10d～ 3个月后进行介入化疗尽量靠近胰十二指肠上下动脉 ,注入 5氟尿嘧啶 (5 FU) 1～ 1.5g ,丝裂霉素 8～ 14mg、顺铂 40～ 6 0mg ,生长抑素 1U。 3周后进行手术。结果 16例肿瘤均得以切除 ,其中常规胰十二指肠切除 7例 ,区域性胰十二指肠切除 9例 ,其中 3例取人造血管行门静脉架桥术 ,4例切除血管后行对端吻合、2例做部分血管壁切除后修补。结论 “3阶段法”治疗大胰头癌是可行的 ,手术安全 ,效果好。
Objective To evaluate the feasibility and effectivity of “3 steps procedure” in the treatment of large pancreatic head cancer. Methods The “3 steps procedure” consisted of decompression of jaundice by simple cholecystotomy, intervenient (intra arterial) chemotherapy (5 FU 1～1.5 g, mitomycin 8～14 mg, cisplatin 40～60 mg and octreatide 1 μ intravenously as near the superior and inferior pancreatic duodenal arteries as possible), and then the reasonable regional pancreatic duodenectomy. Results All 16 tumors were radically resected. Conventional and regional pancreatic duodenectomy was done in 7 and 9 patients, respectively; of the later group, artificial prothesis for portal vein bridge was done in 3 patients, end to end anastomosis in 4 and repair after partial resection of invaded vessel wall in 2. Conclusion The “3 steps procedure” is feasible and effective in the treatment of large pancreatic head cancer.
出处
《中华医学杂志》
CAS
CSCD
北大核心
2000年第4期252-254,共3页
National Medical Journal of China
关键词
胰腺肿瘤
胰头癌
外科手术
放射疗法
综合疗法
Pancreatic neoplasms
Decompression, surgical
Radiology, intervention
Pancreatcoduodenectomy
