摘要
目的探讨血清降钙素原(PCT)、C-反应蛋白(CRP)、外周血白细胞计数对中枢神经系统感染性疾病的诊断价值。方法采用半定量固相免疫测定法测定31例中枢神经系统感染性疾病患者(细菌性感染组18例,非细菌性感染组13例)血清PCT浓度,免疫散射速率比浊法测定CRP,常规方法检测外周血白细胞。结果血清PCT对中枢神经系统细菌感染诊断的敏感度为100.0%,特异度为76.9%,优于CRP(P=0.001),与白细胞计数阳性率比较,差异无统计学意义(P>0.05)。结论血清PCT测定是中枢神经系统细菌感染的有效指标。
Objective To evaluate the diagnosis value of serum procaleitonin （ PCT）, C - reactive protein（CRP） and white blood eel] （WBC） in patients with central nervous system infection. Methods Serum PCT was determined by semi - quantitative solid - phase immunoassay from 31patients with central nervous system infection（ 18 with bacterial and 13 with non -bacterial）. CRP was measured by using immunity - turbidity method and WBC was counted by routine method. Results The sensitivity of PCT was 100.0% and the specificity was 76.9% for the diagnosis of patients with bacterial central nervous system infection . There was no significant difference between PCT and WBC （ P = 0. 673 ）, PCT had higher sensitivity and specificity than CRP（P=0.001）. Conclusions Serum PCT is an effective indication of bacterial central nervous system infection .
出处
《中国医师进修杂志（内科版）》
2006年第7期22-23,共2页
Chinese Journal of Postgraduates of Medicine
关键词
降钙索原
C-反应蛋白
中枢神经系统感染
细菌感染
Procaleitonin
C -reactive protein
Central nervous system infection
Bacterial infection
