摘要
目的探讨炎症和机体免疫反应与冠心病(CHD)之间的相关性。方法设立病例组与正常对照组,病例组选取经冠状动脉造影证实为CHD的患者80例,包括心肌梗死(AMI)组26例,不稳定型心绞痛(UP)组24例,稳定型心绞痛(SP)组30例;正常对照组为30例体检健康者。分别测定所有研究者的血清C-反应蛋白(CRP)、IgG、IgA、IgM等指标。结果AMI组和UP组的CRP、IgG、IgA水平与对照组比较,差异有统计学意义(P<0.05或P<0.01);AMI组、UP组和SP组的IgM水平,SP组的CRP、IgG水平与对照组比较,差异均无统计学意义(P>0.05)。结论CHD与炎症和机体免疫系统的激活密切相关。
Objective To assess the correlation between inflammation, specific immune response and coronary heart disease（CHD）. Methods Thirty healthy cases passed the health examination were taken as the control group. Eighty cases who were diagnosised into CHD, affirmed by coronary angiography, were divided into three groups： acute myocardial infarction （AMI） group （26 cases）, unstable angina pectoris （UP） group （24 cases） ,and stable angina pectoris （SP） group（30 cases）. All the cases were tested on the concentrations of C -reactive protein（CRP）, IgA, IgG, IgM in serum. Results The serum indices of CRP,IgG,IgA in AMI group and UP group were significantly difference than those in the control group （ P 〈 0.05 ）, but there was no significant difference in the indices of IgM in UP group, SP group and AMI group,and the indices of CRP,IgG of the SP group than that in the control group （P 〉 0.05）. Conclusion The correlation between inflammation and immune system activation are closely associated with CHD.
出处
《中国医师进修杂志（内科版）》
2006年第7期17-18,21,共3页
Chinese Journal of Postgraduates of Medicine
关键词
冠心病
炎症
免疫反应
C-反应蛋白
免疫球蛋白
Coronary heart disease
Inflammation
Immunity
C - reactive protein
Immunoglobulin
