摘要
建立了高效液相色谱-质谱法同时测定生鲜牛奶中杀线威、涕灭威残留量的方法。样品用乙酸乙酯提取，C18固相萃取柱纯化、富集，采用电喷雾正离子模式离子化。在质谱图中。[M＋Na]^＋强度最大。定量测定使用多离子监测模式m／z：242→72，213→116。杀线威、涕灭威的检测限分别为0．4ng、0．1ng，方法的平均回收率：杀线威为92．5％-95．6％、涕灭威为91．6％-93．4％。方法的灵敏度高，选择性好。用于实际样品的分析，获得满意的效果。
A liquid chromatographic method, with elcctrospray ionization tandem mass spectrometry （ LC - ESI - MS/MS）, has been developed for simultaneously determining Oxamyl and Aldicarb in milk. The sample was extracted by ethyl acetate, and purified by C18, The most prominent ion in ESI - MS spectra were [ M ＋ Na ] ^＋ , The mass spectrometer was operated in the positive mode using multiple reaction monitoring m/z：242→72,213→116 for qualitative and quantitative analysis of these compounds at the same time. The limits of detection（LOD） of Oxamyl and Aldicarb were 0.4ng and 0. lng; and average recoveries ranged from 92.5% - 95.6% to Oxamyl and 91.6% - 93.4% to Aldicarb. The advantages of the method are sensitive and high selection. The method is applied to detect the residues in real sample with satisfactory results.
出处
《江西科学》
2006年第3期242-244,248,共4页
Jiangxi Science
关键词
高效液相色谱-电喷雾电离质谱
氨基甲酸酯农药
牛奶
残留
High performance liquid chromatography - electrospray ionization mass spectrometry, Carbamate pesticides, Milk, Residues
