摘要
大鼠预饲高脂饲料（占日摄入热量的２０％、３５％和４５％）１月后，进行急性（－１５℃，２ｈ和慢性（０℃，３ｗｋ）冷暴露。测定心肌线粒体细胞色素Ｃ氧化酶（ＣＣＯ）及肝线粒体脂蛋白脂酶（ＬＰＬ）活性及耐寒力。结果如下：（１）急性冷暴露组ＣＣＯ及ＬＰＬ活性明显高于慢性冷暴露组及室温对照组（Ｐ＜０．０１）。慢性冷暴露组的ＬＰＬ活性亦高于室温对照组。（２）０℃、８ｈ冷暴露时直肠温度下降幅度明显小于食用普通低脂饲料的大鼠（Ｐ＜０．０１）。（３）２０％和３５％脂肪组在０℃、３ｗｋ慢性冷暴露过程中，体重的恢复早于４５％脂肪组。结果提示预饲１个月高脂饲料，有利于提高耐寒力和加速冷适应，脂肪产热比以２０％～３０％为宜。
ats fed with high-fat diet (20%,35%and 45%of daily energy intake)for l month underwent two types of cold exposure.e.g.acute exposure to-15℃ for 2h and to 0℃ for 3wks.Activities of cardiac mitochondria cyto-chrome C oxidase (CCO)and hepatic mitochondria lipoprotein lipase (LPL)and cold tolerance were tested.The results were as follows:(1)Activities of CCO and LPL during acute cold exposttre increased significantly thanchronic exposure and room temperature control(P<0.01.Chronic cold ex-posure also enhanced LPL activity over that of room temperature control.(2)Fall of rectal temperature during 0℃ 8h cold exposure was lesser than that of rats kept on low-fat routine diet(P<0.01).(3)While exposed to 0℃ for 3wks,body weights of 20%and 35%fat groups restinled normal levelmore promptly than that of 45%fat group.It suggested that pre-fed with high-fat diet (up to 20%-30%of daily energy intake)may improve cold tolerance and speed up cold acclimatization in rats.
出处
《解放军预防医学杂志》
北大核心
1996年第3期174-177,共4页
Journal of Preventive Medicine of Chinese People's Liberation Army
关键词
冷暴露
高脂膳食
细胞色素C
氧化酶
脂蛋白脂酶
cold exposure
high-fat diet
cytochrome C oxidase(CCO)
lipoprotein lipase (LPL)
cold tolerance
