摘要
用８０只９日龄ｗｉｓｔａｒ大鼠仔鼠，以腹腔注射法，研究了胆碱（Ｃｈｏ）、酪氨酸（Ｔｙｒ）和色氨酸（Ｔｒｐ）对仔鼠抗冷应激能力的影响。结果表明：Ｃｈｏ５０ｍｇ·ｋｇ－１组，Ｔｙｒ２５、５０、７５ｍｇ·ｋｇ－１组，Ｔｒｐ５０、７５、１００ｍｇ·ｋｇ－１组腹腔注射３０ｍｉｎ后的机体产热量比处理前提高５．６０％～６２．６０％，比对照组（ＣＲ）组高１５．３８％～１７３．４５％；仔鼠在移入４～６℃环境下１ｈ后，Ｃｈｏ组仔鼠的口腔温度下降值均大于ＣＲ组，Ｔｙｒ组２５ｍｇ·ｋｇ－１（Ｐ＜０．０５），色氨酸５０ｍｇ·ｋｇ－１、７５ｍｇ·ｋｇ－１（Ｐ＜０．０１）、１００ｍｇ·ｋｇ－１（Ｐ＜０．０１）口腔温度下降值均小于ＣＲ组；利用最小二乘法建立数学模型模拟该条件下仔鼠口腔温度的变化趋势表明，Ｃｈｏ１００ｍｇ·ｋｇ－１组，Ｔｙｒ２５ｍｇ·ｋｇ－１组、Ｔｒｐ５０、７５和１００ｍｇ·ｋｇ－１组具有较好的抗冷应激效果。
Eighty wistar neonatal rats at 9d of age were randomly assigned toinvestigate the effects of treatment with choline,tyrosine or tryptophan on cold-stress-resistant at ambient temperature of 4-6℃. The results showed that thequantity of heat production of 50mg·kg -1 choline treatment,25mg·kg -1 ,50mg·kg -1 ,75mg·kg -1 tyrosine treatment and 50mg·kg -1 ,75mg·kg -1 ,100mg·kg -1 tryptophantreatment after intraperitonal injection (ip) 30 min were higher than that beforetreatment, and 5.43-173.46% higher than that of controls. The oral temperaturedecrease values of 25mg·kg -1 tyrosine treatment was lower (P <0.05) than that ofthe control, of 50mg·kg -1 ,75mg·kg -1 ,100mg·kg -1 tryptophan treatment were lower(of which 75mg·kg -1 P<0.01,100mg·kg -1 P<0.01) than that of the control at 1h ofcold exposed respectively.
出处
《黑龙江八一农垦大学学报》
1997年第3期69-73,共5页
journal of heilongjiang bayi agricultural university
