期刊文献+

带有力学调控系统的各向异性骨再造模型 被引量:3

Anisotropic Bone Remodeling Model with Mechanostat
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摘要 目前,骨再造数值模型在生理上和力学上都不能复制骨再造的实际生理过程。本文引入了骨再造的生理机制和骨力学性质的各向异性,在损伤修复理论的基础上,建立了带有力学调控系统的各向异性骨再造模型,使骨再造的数值模拟趋向和生理过程一致,并以二维方板模型为例进行了计算机模拟,得到了和实际较为一致的结果。本模型可用于在一定力学环境下或力学环境改变后,骨结构的模拟,还可用于植入物植入后骨结构发生结构变化的模拟。 At present, the numerical model of bone remodeling is inadequate to copy the physiological process of bone remodeling. According to the physiological mechanism of bone remodeling and the anisotropy of bone mechanics properties, an anisotropic bone modeling model with mechanostat was developed, and then was applied to a study on the remodeling evolution of 2D squareplate model. Good results were obtained. The model can be used in the study of implant,osteoporosis and other bone diseases.
出处 《生物医学工程学杂志》 EI CAS CSCD 北大核心 2006年第3期525-529,共5页 Journal of Biomedical Engineering
基金 国家自然科学基金资助项目(10372034) 博士点基金资助项目(20020183026) 吉林省科技发展计划项目(200505215)
关键词 力学调控系统 各向异性 损伤修复理论 骨再造模型 Mechanostat Anisotropic Damage-repair theory Bone remodeling model
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参考文献13

  • 1Frost HM.Why the ISMNI and the Utah paradigm? Their role in skeletal and extraskeletal disorders,J Musculoskel Neuron Interact,2000; 1:5
  • 2Frost HM.The Utah paradigm of skeletal physiology:an overview of its insights for bone,cartilage and collagenous tissue organs.J Bone Miner Metab,2000;18:305
  • 3Jee WSS.Principle in bone physiology.J Musculoskel Neuron Interact,2000;1:11
  • 4Mullender MG,Huiskes R,Weinans H.A physiological approach to the simulation of bone remodeling as a self-organizational control process.J Biomechanics,1994;27(11):1389
  • 5Garcнa JM,Martнnez MA,Doblarй M.An anisotropic internal-external bone adaptation model based on a combination of CAO and continuum damage mechanics technologies.Computer Meth Biomech Biomed Eng,2001;4(4):355
  • 6Doblarй M and Garcнa JM.Application of an anisotropic bone remodelling model based on a damage repair theory to the analysis of the proximal femur before and after total hip replacement.J Biomech,2001; 34(9):1157
  • 7Doblarй M and Garcнa JM.Anisotropic bone remodelling model based on a continuum damage-repair Theory.J Biomech,2002; 35(1):1
  • 8张毅奕,陶祖莱.载荷诱导骨生长的力学细胞生物学机制[J].力学进展,2000,30(3):433-445. 被引量:19
  • 9Martin RB.Porosity and specific surface of bone.CRC Critical Reviews Biomed Engineer,1984;10(3):179
  • 10Carter DR.Mechanical loading historyand skeletal biology.Journal of Biomechanics,1987;20:1095

二级参考文献29

  • 1王颖坚.松质骨的细观力学研究评述[J].力学进展,1996,26(3):416-423. 被引量:22
  • 2朱兴华,白凤德,董心,王晓迎.三面固定槽形加压钢板内固定后股骨表面再造模拟[J].中国生物医学工程学报,1997,16(2):128-132. 被引量:14
  • 3Hung C T,J Biomech,1996年,29期,141l页
  • 4Duncan R L,Proc Nat Acad Sci SUA,1996年,93期,1864页
  • 5Duncan R L,CalcifTiss Int,1995年,57期,344页
  • 6Harter L V,Endocrinology,1995年,136期,528页
  • 7Malek A M,J Biomech,1995年,28期,1515页
  • 8Burr D B,Trans Orthop Res Soc,1995年,20期,202页
  • 9Damoulis P D,Biochem Biolphys Res Commun,1994年,201期,924页
  • 10Weinbaum S,J Biomech,1994年,27期,339页

共引文献24

同被引文献25

  • 1孟繁杰,史晨辉.uPA/uPAR/PAI系统在膝骨性关节炎中的应用研究进展[J].中国现代医药杂志,2010(7):122-124. 被引量:3
  • 2吕红岩,何欣,郝利铭.影响骨形态发育因素研究[J].北华大学学报(自然科学版),2007,8(4):314-321. 被引量:1
  • 3Tezuka K,Wada Y,Takahashi A,et al.Computer-simulated bonearchitecture in a simple bone-remodeling model based on reaction-diffusion system[J].J Bone Miner Metab,2005,23(1):1-7.
  • 4Wolff J.The law of bone remodelling[M].Berlin:Springer-Verlag,1986:1-126.
  • 5Lengyel I,Epstein IR.Modeling of turing structures in the chlorite-iodide-malonic acid-starch reaction system[J].Science,1991,251(4994):650-652.
  • 6Mullender MG,Huiskes R,Weinans H.A physiological approachto the simulation of bone remodeling as a self-organizational controlprocess[J].J Biomechanics,1994,27(11):1389-1394.
  • 7Forst HM.The Utah paradigm of skeletal physiology:an overview ofits insights for bone,cartilage and collagenous tissue organs[J].JBone Miner Metab,2000,18(6):305-316.
  • 8Huiskes R,Ruimerman R,van Lenthe GH,et al.Effects ofmechanical forces on maintenance and adaptation of form in trabecu-lar bone[J].Nature,2000,405(6787):704-706.
  • 9Christie A,Martin M,Williams EL,et al.The estimation of fetalmaturity by roentgen studies of osseous development[J].Am JObstet Gynecol,1950,60(1):133-139.
  • 10Robinson HP.Sonar measurement of fetal crown rump length asmeans of assessing maturity in first trimester pregnancy[J].Br MedJ,1973,4(5883):28-31.

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