摘要
目的研究从胚胎期到成熟过程中股骨形成、生长和成形规律,分析骨生长中心形成、骨质层体积及骨形变化规律。方法采用CT扫描技术定期扫描新西兰兔股骨生长过程并获取图像信息,用Mimics医学图像处理软件分析CT扫描断层图像信息。利用骨元体积法对股骨成形及其骨质层的变化过程进行时间分段和空间分层分析,分析股骨形成过程及骨质层体积变化规律。结果股骨有多个骨生长中心。胚胎里股骨最早以软质骨的形式出现,随着生长逐渐硬化形成密质骨和硬质骨,最后形成最佳的股骨形状和骨质分布。结论股骨由独立的4个骨生长中心发育并组合而成;各骨质层在生长过程中存在明显的体积和位置变化,但最终趋于稳定状态。
Objective To observe the rule of formation,growth and figuration of femur in the process from embryonic development to maturation,and analyse the formation of bone growth center,volume of bone layer and variation of bone shape.Methods CT scan technology was employed to obtain the imaging information of femur development process of rabbits,and the CT imaging information was processed with Mimics Medical Image Processing software.Time-phase and stratified space analysis of rule of femur figuration and variation of volume of bone layer were performed with unit bone volume method.Results Femur has multiple bone growth centers.The femur bone first emerged as spongy bone during embryonic process,and gradually got harden and formed the compact bone and enamel bone along with the growth.Finally,the femur bone developed its optimal shape and bone mass distribution.Conclusion The femur is developed by combination of 4 independent bone growth centers.There is obvious change in volume of bone layer and position in the process of bone growth,while stabilized state is eventually arrived.
出处
《上海交通大学学报（医学版）》
CAS
CSCD
北大核心
2012年第3期263-268,共6页
Journal of Shanghai Jiao tong University:Medical Science
基金
国家自然科学基金(50775193
50805125
81160542)
新疆维吾尔自治区科技厅基金(201123113)
青年教师科研培育基金(XJED2009S55)~~
关键词
股骨
生长与发育
骨质层
骨生长中心
femur
growth and development
bone layer
bone growth center
