摘要
1994年9月至1995年8月我们以泰素、顺铂治疗晚期恶性肿瘤14例,6例获PR(44%)。主要毒性为骨髓抑制,白细胞减少、贫血和血小板减少的发生率分别为64%、71%和36%,以Ⅰ、Ⅱ度毒性为主,无发热和感染。肌肉关节酸痛见于44%受治者。其他毒性少见。未见过敏反应。
Fourteen cases of advanced malignant tumors were treated by Taxol 180mg d1 with premedication plus DDP 40mg d2 ̄4 from Sept.1994 to August 1995.Six partial responses(44%)have been observed.Myelosuppresion is the principal toxicity,which is mainly of Ⅰ,Ⅱgrade.No toxicity of Ⅲ grade is observed.The rate of leukopenia,anemia,and thrombocytopenia is 64%,71%,and 36 % respectively.There is neither febreile nor infection.The rate of myalgia and arthralgia is 44%.There is no hypersensitivity reaction.
出处
《河南肿瘤学杂志》
1996年第2期106-108,共3页
Henan Journal of Oncology