摘要
目的:通过对乙肝病人血清抗-HBcIgA、HBcIgE、HbcIgG、HbcIgM平行检测进一步地探讨其临床应用价值。方法:收集216份乙肝病人血清(均为我院住院病人的血清),采用ELISA法对病人血清抗-HBcIgA、HBcIgE、HBcIgG、HBcIgM平行检测,并对检测结果作统计学分析。结果:检测结果表明:抗-HBcIgA是HBV感染后肝脏损害的明显标志,抗-HBcIgE是HBV感染后乙型肝炎慢性化的标志,抗-HBcIgG持续存在则是以往感染的标志,抗-HBcIgM是HBV感染后病毒持续复制的标志。结论:在急慢性乙型肝炎、慢活肝与慢迁肝鉴别诊断中,平行检测病人血清抗-HBcIgA、HBcIgE、HbcIgG、HbcIgM对乙型肝炎慢性化及其预后估价均有重要临床意义。
Objective： To further study the clinical application value of parallel examination of anti - HBcIgA, HBcIgE, HBcIgG and HBcIgM in the sera of patients with hepatitis B（HB）. Methods： 216 blood specimens of HB patients, who were in- patients in our hospitat,were collected and examined. And the levels of anti- HBcIgA, HBcIgE, HBcIgG and HBcIgM in the sera of the patients were statistically analysed. Results： The results showed that anti - HBcIgA was the identification marker of liver lesion post infection of HBV, anti - HBcIgE wa the chronicity marker of HB post infection of HBV, anti - HBcIgG persistence existence was the infection marker in the past, and anti - HBcIgM was the marker of virus persistence replication post infection of HBV. Conclusion： In the differential diagnosis of acute or chronic HB, ctronic active hepatitis and chronic persistent hepatitis, parallel examining anti - HBcIgA, HBcIgE, HBcIgG and HBcIgM in the sera of the patients will he a significant means for HB chronieity and prognasis.
出处
《现代生物医学进展》
CAS
2006年第3期29-30,共2页
Progress in Modern Biomedicine
