摘要
目的了解本地区尿石患者支原体感染状况及流行特点,为临床治疗提供参考依据。方法对423例尿石患者的结石标本进行支原体培养和药敏试验以及尿石化学成分分析。结果解脲脲原体(Uu)阳性90例(21.3%),人型支原体(Mh)阳性1例(0.2%),Uu合并Mh阳性11例(2.7%),共102例(24.1%)。感染的年龄段主要分布在30～39岁(阳性率为24.5%)、40～49岁(阳性率为19.6%)和50～59岁(阳性率为31.4%);189例女性患者支原体阳性为59例(31.2%),234例男性患者支原体阳性为43例(18.3%),女性感染率明显高于男性(P<0.01)。对强力霉素敏感率为81.5%,四环素敏感率为64.7%,交沙霉素、红霉素、阿齐霉素、原始霉素敏感率分别为44.6%、42.1%、47.8%、45.3%,氧氟沙星、环丙沙星为29.5%和26.5%。其尿石的主要成分为磷酸钙,草酸钙以及尿酸盐,多见于肾和输尿管。结论本地区尿石中的支原体感染以Uu感染为主,检出率达23.98%,好发年龄在30～59岁之间,女性明显高于男性(P<0.01),并对多种抗生素已产生耐药性,强力霉素可作为治疗尿结石中支原体感染的首选药物。
Objective To examine the prevalent characteristic of Mycoplasrna in patients with urolithiasis in our district. To provide clinical data for the treatment of urolithiasis. Method A total of 423 samples from patients with urolithiasis were analyzed for mycoplasma infection. Antibiotic susceptibility test and chemical analysis were also conducted. Result There were 102 patients who were found to have infection by Ureaplasma urealyticurn （Uu） or Mycoplasma hominls （Mh）,positive rate was 24.1%. 90 patients （21.3%） were found to have infection by Uu. 1 patient （0.2%） had the infection of Mh. 11 patients （2.7%） had Uu and Mh. The age group distribution of the infected patients was 30 to 39（24.5%）, 40 to 49（19.6%） and 50 to 59（31.4%）. Among the 189 female patients, 59（31.2%） were found to have mycoplasma. Among the 234 male patients, 43（18.3%） were infected by myeoplasma. The percentages of isolates sensitive to the action of antibiotics are 81.5% for dosycycline, 64.7% for tetracyclin, 44.6% for Josamyxcin, 42.1% for Erythromycin, 47.8% for Azithromycin, 45.3% for Pristinamycin, 29.5% for Ofloxacin, 26.5% for Ciprofloxacin. Oxalate, phosphate and uric acid salt are the major chemical composition of urolite. Conclusion Un is the major type of Mycoplasma in patients with urolithiasis in this district. Most of the patients with Uu infection are in the age of 30 to 59, and the incidence in female ishigher than in male （P〈0.01）. Most of the Mycoplasma are multidrug-resistant. Dosycycline should be considered as the frist line antibiotic used for the treatment of patients with Mycoplasma.
出处
《热带医学杂志》
CAS
2006年第4期419-421,共3页
Journal of Tropical Medicine
关键词
尿结石
支原体
药敏试验
化学成分
urolithiasis
Mycoplasma
antibiotic susceptibility testing
chemistry component
