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代谢综合征患者大动脉顺应性变化的探讨 被引量：1

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摘要 目的:探讨代谢综合征患者大动脉顺应性的变化。方法:118例代谢综合征患者和65例年龄相匹配的正常对照者,应用脉搏波速度(PWV)测定仪对所有入选者测定颈动脉-股动脉的脉搏波速度(C-FPWV),同时检测其身高、体重、腰围、臀围、血压、血糖、血脂、尿酸水平,并计算体重指数(BMI)、腰臀比。结果:代谢综合征患者C-FPWV和正常对照组相比明显升高[(9.8±1.4)m/svs(8.4±1.5)m/s,P<0.01]。Pearson相关分析显示代谢综合征患者C-FPWV与年龄、收缩压、脉压、BMI、总胆固醇、甘油三酯、尿酸呈显著正相关(分别为r=0.46,r=0.29,r=0.26,r=0.22,r=0.27,r=0.31,r=0.33;P均<0.01),与体重呈正相关(r=0.19;P<0.05),与高密度脂蛋白胆固醇呈显著负相关(r=-0.23;P<0.01)。结论:(1)代谢综合征患者C-FPWV明显升高,已经存在动脉顺应性的减退;(2)代谢综合征患者大动脉顺应性的变化与年龄、血压、肥胖及血脂紊乱有关。
作者 闵新文 李东锋 汤天军 陈欣 赵黎炳 杨汉东
机构地区 郧阳医学院附属东风医院心内科
出处 《实用医学杂志》 CAS 2006年第9期1016-1018,共3页 The Journal of Practical Medicine
关键词 代谢综合征 动脉 脉搏波速度 大动脉顺应性变化
分类号 R589 [医药卫生—内分泌]
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参考文献11

  • 1ASMAR R, BENETORS A, TOPOUCHIAN J, et al. Assessment of arterial distensibility byautomatic pulse wave velocity measurement validation and clinical applieationstudias [ J ]. Hypertension, 1995, 26(3):485 -490.
  • 2Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults. Executive summary of the third report of the national cholesterol education program (NECP) expert panel ondetection, evaluation, and treatment of high blood cholesterol in adults (Adult Treatment Panel Ⅲ) [J]. JAMA, 2001, 285(19):2486 - 2497.
  • 3中国肥胖问题工作组.中国成人超重和肥胖症预防与控制指南(节录)[J].营养学报,2004,26(1):1-4. 被引量：1933
  • 4LEGEDZ L, RIAL M O, LANTELME P, et al. Markers of cardiovascular remodeling inhypertension [J ]. Arch Mal Coeur Vaiss,2003, 96(7/8): 729 - 733.
  • 5ISOMAA B, ALMGREN P, TUOMI T, et al. Cardiovascular morbidity and mortalityassocisted with the metabolic syndrome [J].Diabetes Care, 2001, 24(4): 683 -689.
  • 6ZIMMET P, BOYKO E J, COLLIER G R, et al. Etiology of the metabolic syndrome: potential role of insulin resistance, leptin resistance, and other playees [J]. Ann N Y Acad ,Sci, 1999, 892:25 -44.
  • 7BARZILAI N, GUPTA G. Interaction between aging and syndrome X:new insights on thepathophysiology of fat distribution [J]. Ann N Y Acad Sci, 1999, 892:58 - 72.
  • 8李东锋,杨汉东,杨波,汤天军,闵新文,陈欣,赵黎炳.代谢综合征患者血清瘦素与血脂、肥胖及胰岛素抵抗关系的研究[J].实用医学杂志,2005,21(17):1911-1913. 被引量：8
  • 9MACKEY B. Correlates of aortic stiffness by carotid femoral pulse wave velocityin a subgroup of the cardiovascular heath study [J].Circulation, 1998, 98(8): 828.
  • 10倪永斌,张维忠,王宏宇,吴美枝.3156例原发性高血压脂肪分布与大动脉缓冲功能关系研究[J].中国循环杂志,2001,16(2):106-108. 被引量：22

二级参考文献19

  • 1Campfield LA, Smith FJ, Guisez Y, et al. Recombinant mouse OB protein: evidence for a peripheral signal linking adiposity and central neural networks. Science, 1995, 269(5223): 546 - 549.
  • 2Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Aduhs. Exeeutive Summary of The Third Report of The National Cholesterol Education Program (NCEP)Expert Panel on Detection, Evaluation, And Treatment of High Blood Cholesterol In Adults (Adult Treatment Panel Ⅲ ) . JAMA,2001, 285(19): 2486 - 2497.
  • 3Isomaa B, almgren P, Tuomi T, et al. Cardiovascular morbidity and mortality associated with the metabolic syndrome. Diabetes Care,2001, 24(4): 683 - 689.
  • 4Zimment P, Boyko E J, Collier GIL et aL Etiology of the metabolic syndrome: potential role of insulin resistance, leptin resistance, and other player. Ann N Y Acad Sci, 1999, 892:25-44.
  • 5Barzilai N, Gupta G. Interaction between aging and syndrome X:new insight on the pathophysiology of fat distribution. Ann N Y Acad Sci, 1999, 892(8): 58 -72.
  • 6Lofgren I, Herron K, Zern T, et al. Waist circumference is a better predictor than body mass index of coronary heart disease risk in overweight premenopausal women. J Nutr, 2004, 134(5):1071 - 1076.
  • 7Kieffer TJ, Habener iF. The adipoinsular axis: effects of leptln on pancreatic beta-cells. Am J Physiol Endocinol Metab, 2000, 278(1):E1-E14.
  • 8Wabitsch M, Jensen PB, Blum WF, et al. Insulin and cortisol promote leptin production in cultured human fat cells. Diabetes,1996, 45(10): 1435 - 1438.
  • 9Seufert J, Kieffer TJ, Leech CA, et al. Leptin suppression of insulin secretion and gene expression in human pancreatic islets:implications for the development of adipogenie diabetes mellitus. J Clin Endoerinol Metab, 1999,84(2):670-676.
  • 10Kojima M, Kangawa K. Ghrelin: a novel grewth-hormone releasing poptide. Nippon Rinsho, 2001, 59(7): 1400 - 1407.

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实用医学杂志
2006年 第9期

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