摘要
目的了解叙永县高脂血症(hyperlipidemia,HLP)的流行情况,并通过广义估计方程(generalized estimating equations,GEE)探讨成年人患HLP的影响因素,为制定针对欠发达地区成年人HLP的防治策略提供科学依据。方法对叙永县2017—2021年参与≥2次健康体检成年人的体检数据进行统计分析,采用GEE分析城乡、体质量指数(body mass index,BMI)、中心型肥胖、心率、吸烟、锻炼对HLP检出率的影响。结果共纳入142770例研究对象,共提取425930条符合纳入标准的成年人体检相关信息,平均年龄(62.49±13.37)岁,女性偏多,共78719例(55.14%)。叙永县成年人2017—2021年的HLP检出率分别为36.86%、38.31%、37.62%、39.17%、38.40%。经GEE分析,在控制相关混杂因素后,肥胖[OR=1.919,95%CI(1.846~1.995)]、超重[OR=1.618,95%CI(1.579~1.658)]、年龄≥65岁[OR=1.533,95%CI(1.383~1.699)]、年龄35~64岁[OR=1.504,95%CI(1.358~1.667)]、中心型肥胖[OR=1.450,95%CI(1.411~1.491)]、锻炼[OR=1.261,95%CI(1.214~1.309)],女性(参照男性)[OR=1.207,95%CI(1.169~1.246)]、心率>80次/min(参照心率70~80次/min)[OR=1.193,95%CI(1.154~1.234)]、文化高中及中专组[OR=1.189,95%CI(1.111~1.272)]、戒烟[OR=1.143,95%CI(1.074~1.215)]、吸烟[OR=1.098,95%CI(1.061~1.137)]是成年人患HLP的危险因素(P<0.001)。偏瘦[OR=0.598,95%CI(0.565~0.633)]、农村[OR=0.709,95%CI(0.677~0.742)]、心率<70次/min[OR=0.864,95%CI(0.843~0.885)]、已婚[OR=0.923,95%CI(0.865~0.983)]是成年人患HLP的保护因素(P<0.05)。结论四川省叙永县成年人的HLP检出率较高,建议对具有多项危险因素的居民进行早期健康监测,从而制定更具有针对性的健康管理方法,以达到预防HLP的目的。
Objective To understand the prevalence of hyperlipidemia in Xuyong County,and to explore the influencing factors of adult hyperlipidemia through generalized estimating equations(GEE),so as to provide scientific basis for formulating prevention and treatment strategies for adult hyperlipidemia in less developed areas.Methods The physical examination data of adults participating in physical examination in Xuyong County from 2017 to 2021 were statistically analyzed.The GEE was used to analyze the impact of urban and rural areas,body mass index(BMI),central obesity,heart rate,smoking,and exercise on the detection rate of hyperlipidemia.Results A total of 142770 adults were included,and a total of 425930 pieces of adult physical examination related information that met the inclusion criteria were extracted.The average age was(62.49±13.37),with more females,totaling 78719(55.14%).The detection rate of hyperlipidemia among adults in Xuyong County from 2017 to 2021 was 36.86%、38.31%、37.62%、39.17%、38.40%respectively.According to GEE analysis,after controlling for related confounding factors,obesity[OR=1.919,95%CI(1.846-1.995)],overweight[OR=1.618,95%CI(1.579-1.658)],age≥65 years old[OR=1.533,95%CI(1.383-1.699)],age 35 years old to 64 years old[OR=1.504,95%CI(1.358-1.667)],central obesity[OR=1.450,95%CI(1.411-1.491)],exercise[OR=1.261,95%CI(1.214-1.309)]Women(referring to males)[OR=1.207,95%CI(1.169-1.246)],heart rate>80 beats/min(referring to heart rate 70 to 80 beats/min group)[OR=1.193,95%CI(1.154-1.234)],educated high school and vocational school groups[OR=1.189,95%CI(1.111-1.272)],smoking[OR=1.143,95%CI(1.074-1.215)],and smoking[OR=1.098,95%CI(1.061-1.137)]are risk factors for adult hyperlipidemia(P<0.001).Slimming[OR=0.598,95%CI(0.565-0.633)],rural[OR=0.709,95%CI(0.677-0.742)],heart rate<70 beats/min[OR=0.864,95%CI(0.843-0.885)],married[OR=0.923,95%CI(0.865-0.983)],are protective factors for adult hyperlipidemia(P<0.05).Conclusions The detection rate of hyperlipidemia and hyperlipidemia among adults in Xuyong County,Sichuan Province is high.It is suggested to carry out early health monitoring for residents with multiple risk factors,so as to develop more targeted health management methods to prevent hyperlipidemia.
作者
张冠华
李正业
刘亚南
李爱玲
ZHANG Guan-hua;LI Zheng-ye;LIU Ya-nan;LI Ai-ling(School of Public Health,Southwest Medical University,Luzhou,Sichuan 646000,China;不详)
出处
《慢性病学杂志》
2024年第7期973-980,共8页
Chronic Pathematology Journal
基金
四川省卫生健康委员会科研课题全民预防保健项目——对贫困地区重大慢性病防控效果评价及项目优化研究(20PJ319)
关键词
高脂血症
广义估计方程
纵向数据研究
流行
Hyperlipidemia
Generalized estimation equation
Longitudinal data research
Prevalence
