摘要
目的测定乙肝灵胶囊中芍药苷的含量。方法采用HPLC法,色谱柱采用Beckman C18反相柱。流动相:甲醇-0.05mol.L-1磷酸二氢钾溶液-醋酸-异丙醇(67∶173∶4∶4),流速为0.8ml.min-1,检测波长为240nm。结果本法线性关系良好(r=0.9995),平均加样回收率为98.44%,RSD=0.77%(n=6)。结论本法简便易行,结果准确,重现性好,可用于乙肝灵胶囊的质量控制。
OBJECTIVE Determination of Yigan Ling Capsule by HPLC. METHODS The Beckman C18 column was used,methanol-0. 05mol·L^-1 potassium phosphate dibasic soluition-acetic acid-isopentanol（67：173： 4：4）were as mobile phase,flow rate was 0. 8ml·min^-1 ,detection wavelength was at 240nm. RESULTS The method had a good linear dependence （ r =0. 9995） ,average recovery was 98.44% ,and RSD was 0.77%（ n =6）. CONCLUSION The method is simple,rapid,accurate and reliable, and can be used for quality control of Yigan Ling Capsule.
出处
《齐鲁药事》
2006年第4期220-221,共2页
qilu pharmaceutical affairs
