摘要
系统性红斑狼疮(SLE)很常见,以肾脏受累为第一个表现难以诊断。本文分析111例SLE中以肾脏病为首发表现者22例(占20％)。狼疮性肾炎(LN)为SLE的首发表现常以肾病综合征(NS)为主,其病理主要是膜性和弥漫增殖性。血C_3下降、γ球蛋白与ANA升高和贫血有助于鉴别。LN急性发作、肾功能恶化、活动病变用MP冲击治疗预后好。
SLE is a quite common disease in China. This paper analyzed 111 SLE cases, among them, 22 cases (20％) had their initial clinical manifastation as renal disease alone. This raised difficulty in the diagnosis of SLE. Membranous lupus glomerulonephritis (LN) and diffuse proliferative LN were the main pathologic lesions of SLE, and most of them preheated as nephrotic sysdrome (NS). Increased serum γ-globulin, decreased serum C_3, positive antinuclear antibody (ANA) and anemia were helpful for the recognition of SLE. Acute ontset, progressive renal failure and activity of SLE had a favorable response to methylprednisone pulse therapy.
出处
《北京医学》
CAS
北大核心
1990年第1期4-6,共3页
Beijing Medical Journal
