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系统性红斑狼疮89例首发症状及误诊分析 被引量:2

Analysis of initial symptoms and misdiagnosis of 89 systemic lupus erythematosus patients
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摘要 目的研究系统性红斑狼疮(SLE)的首发症状及早期误诊原因,以期提高早期确诊率。方法对89例SLE患者首发症状及早期临床资料进行回顾性分析。结果 89例患者中有38例(42.7%)患者曾被误诊,其中有16例(18%)被误诊两种以上的疾病。误诊的疾病有类风湿性关节炎,风湿性关节炎,干燥综合症,肌炎,皮肌炎,混合性结缔组织病,Still病,血管炎;多形性红斑,日光性皮炎,脂溢性皮炎,过敏性紫癜,药物过敏;肾病综合症,肾炎,肾盂肾炎,膀胱炎;肠梗阻,胰腺炎;上呼吸道感染,淋巴结炎,甲状腺功能减退,白细胞减少症,癫痫,结核等。结论 SLE患者临床表现错综复杂,首发症状无固定模式,医师对该病认识不足和思维局限等是构成SLE早期误诊的主要原因。提高对该病的认识,积极进行相关的检查,可减少早期误诊率。 Objectlve To increase the accuracy of early diagnosis of systemic lupus erythematosus(SLE). Methods The early clinical diagnostic data in 89 SLE cases was analyzed retrospectively. Results 38 (42.7 % )out of 89 cases were misdiagnosed and 16 eases were misdiagnosed more than two diseases, including rheumatoid arthritis, rheumatic fever/rheumatic arthritis, Sjogren' s syndrome, polymyositis, dermatomyositis, mixed connective tissue disease, Still disease, vaseulitis, polymorphous erytbema, solar dermatitis, seborrheie dermatitis, Henoch - Schonlein purpura, drug allergy, nephritic syndrome, nephritis, nephropyelitis, cystitis, ileus, panereatitis, theupper respiratory tract infection, ymphadcnitis, subthyroidism, leukopenia, epilepsy, tubereulosis, and so on. Conclusion The clinical manifestations arc complex and first symptoms are not stable, some doctors didn' t know the features of SLE and their sccope of consideration is limited, those arc main causes of misdiagnosis of SLE.To reduce the early misdiagnostie rate, the recognition of the disease must be improved and the related examinations should be done properly.
作者 方凯华
出处 《中国热带医学》 CAS 2006年第3期453-454,共2页 China Tropical Medicine
关键词 系统性红斑狼疮 首发症状 诊断 误诊 Systemic lupus erythematousus First symptoms Diagnosis Misdiagnosis
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