摘要
目的初步探讨多层螺旋CT(MSCT)血管成像显示颈部动脉狭窄的价值。方法临床可疑或诊断脑供血不足的24例病人行颈部动脉MSCT检查,其结果与导管法颈部动脉造影对照。结果 24例病人共168段颈部动脉中,导管法造影显示正常或轻度狭窄为147段,MSCT对其中的 139段颈部动脉狭窄程度分级与前言一致;导管法造影显示中度或中度以上狭窄(≥30％)为21段, MSCT对其中的19段颈部动脉狭窄程度分级与前者一致,MSCT显示颈部动脉中度和中度以上狭窄的敏感度、特异度、阳性预测值和阴性预测值分别为90．5％、94．6％、70．1％和98．6％。在168段颈部动脉中,导管法造影显示正常、轻度或中度狭窄为156段,MSCT对其中的1 54段颈部动脉狭窄程度分级与前者一致;导管法造影显示高度狭窄或闭塞(≥70％)为12段,MSCT对12段颈部动脉狭窄程度分级与前者一致,MSCT显示颈部动脉重度狭窄和闭塞的敏感度、特异度、阳性预测值和阴性预测值分别为 100％、98．7％、85．7％和100%。结论 MSCT 血管成像显示颈部动脉中、高度狭窄的准确性很高,可以部分替代导管法颈部动脉造影。
Objective To evaluate primarily the accuracy of multislice spiral CT （MSCT） angiography in detecting carotid artery stenosis. Methods A total of 24 consecutive patients with suspected or confirmed carotid artery disease were studied by MSCT （0.6 or 0.5 s rotation time; 1.25 mm thickness; 13.5 mm/s table speed; intravenous contrast agent）. The results were compared with quantitative carotid angiography. Results In the 168 carotid arteries of 24 patients, 19 of 21 carotid arteries with significant stenosis （≥30% reduction of vessel diameter） were correctly detected by MSCT; 139 of 147 normal or slightly stenosed carotid arteries （〈30% reduction of vessel diameter） were correctly detected by MSCT. These values correspond to a sensitivity of 90.5 %, specificity of 94.6 %, positive predictive value of 70.1%, and negative predictive value of 98.6% for the detection of significant carotid artery stenosis by MSCT. In the 168 carotid arteries of 24 patients, 12 of 12 carotid arteries with high-grade stenosis （≥70% reduction of vessel diameter） were correctly detected by MSCT, 154 of 156 carotid arteries without or with low-grade stenosis （〈70% reduction of vessel diameter） were correctly detected by MSCT. These values correspond to a sensitivity of 100 %, specificity of 98.7 %, positive predictive value of 85.7 %, and negative predictive value of 100 % for the detection of high-grade carotid arteries stenosis by MSCT. Conclusion MSCT angiography permits the visualization of significant carotid artery stenosis with high accuracy. It may be used as an alternative for carotid angiography in detecting carotid artery stenosis.
出处
《中华神经医学杂志》
CAS
CSCD
2006年第4期413-415,共3页
Chinese Journal of Neuromedicine
