摘要
目的通过与CT、支气管镜诊断结果的比较,评价CYFRA21-1、神经元特异性烯醇酶(NSE)、癌胚抗原(CEA)联合检测在肺癌诊断中的临床价值。方法对268例明确诊断肺癌患者的CT、支气管镜、CY-FRA21-1、NSE、CEA联合检测结果进行了分析。结果CT、支气管镜、CYFRA21-1、NSE、CEA联合检测三种方法诊断肺癌的灵敏度分别为95.2%、77.6%、90.0%。三种方法联合可以诊断全部肺癌患者。支气管镜诊断中央型肺癌的灵敏度为92.9%,但对于周围型肺癌仅19.6%;CYFRA21-1、NSE、CEA联合检测在周围型和中央型肺癌两组患者中差异无统计学意义。结论①在周围型肺部占位患者中进行CYFRA21-1、NSE、CEA联合检测是必要的;②CT、支气管镜、CYFRA21-1、NSE、CEA联合检测三种方法联合诊断将提高肺癌诊断的灵敏度。
Objective To evaluate the diagnostic value of the combined determination of CYFRA21-1 ,NSE and CEA in lung cancer compared with CT and bronchoscopy examination. Methods All 268 patients with lung cancer were examined by CT, bronchoscopy and combined determiwation of CYFRA21-1, NSE and CEA. Resdls The sensitivity of CT,braneh endoscope and combined determination of CYFRA21-1 ,NSE and CEA for hmg cancer was 95.2% ,77.6% and 90.0%, respectively. All the patients could be diagonosed by combined determination of the 3 methods. The sensitivity of bronehoscopy in central lung cancer was 92.9% ,but in perpeal lung cancer 19.6%. There was no signifieent difference between central lung cancer and perpexal lung eaneex using the combined determination of CYFR,421-1, NSE and CEA. Conclusion OThe combined determination of CYFRA21-1 ,NSE and CEA is necessary for peripheral lung eaneex;（2）The combined diagnosis with the 3 methods will improve the sensitivity for lung cancer.
出处
《山西医药杂志》
CAS
2006年第4期300-301,共2页
Shanxi Medical Journal
