摘要
目的:探讨B型脑钠肽(BNP)对充血性心力衰竭(CHF)诊断的临床意义及不同BNP水平预测CHF的价值。方法:对196例疑似心力衰竭的患者进行快速测定BNP,并同时收集患者其它相关的临床资料,诸如病史、临床症状、体征、胸片等检查结果,比较分析BNP与临床诊断之间的关系,并根据最后诊断将196例患者分为CHF组、肺病组和非CHF非肺病组3组。结果:(1)BNP对CHF预测的准确性高于其它单项临床表现。(2)BNP界值为100pg/ml时,预测CHF的准确性最高。(3)CHF组、肺病组、非CHF非肺病组BNP水平分别为(876.3±669.2)pg/ml、(90.8±110.4)pg/ml、(88.9±130.8)pg/ml,CHF组BNP水平明显高于肺病组和非CHF非肺病组,差异有显著性(P<0.01)。结论:与其它单项临床表现相比BNP值有很高的诊断价值和临床意义。
Objective： To study the clinical significance of B-type natriuretic peptide （BNP） in the diagnosis of congestive heart failure （CHF） and the value of different BNP levels in the prediction of heart failure. Methods： BNP levels were measured with a rapid assay in 196 patients with dyspnea, whose other clinical data such as clinical history,symptoms and signs,X-xay and so on were collected at the same time. The collection of BNP levels and clinical diagnosis were evaluated.The patients were divided into three groups according to the final diagnosis：the CHF group,the pulmonary disease group and neither CHF nor pulmonary disease group. Results： （1） The accuracy of the diagnosis of CHF by BNP was better than other clinical predictors. （2） The BNP cutoff point judged to be optimal for making the diagnosis of CHF was 100 pg/ml. （3） The BNP levels in CHF group , pulmonary disease group and neither CHF nor pulmonary disease group were 876.3±669.2, 90.8±110.4, 88.9±130.8 pg/ml respectively. The BNP levels in CHF group were much higher than other two groups （P〈0.01）. Conclusion： The BNP level plays a very important role in the diagnosis of CHF.
出处
《天津医科大学学报》
2006年第1期105-107,共3页
Journal of Tianjin Medical University
关键词
B型脑钠肽
心力衰竭
诊断
B-type natriuretic peptide
Heart failure
Diagnosis
