摘要
以三氯硫磷、苯唑醇、6-氨基己酸为原料,采用3步反应合成三唑磷半抗原6-[O-乙基-O-(1-苯基-1H-1,2,4-三唑-3-基)硫代磷酰胺基]己酸,经质谱和1H-NMR鉴定表明,合成成功,为进一步制备三唑磷抗体奠定了基础。
This paper reported hapten synthesis and identification of the organophosphate pesticide triazophos. Thiophosphoryl chloride and phenylzole alcohol and 6-aminocaproic acid were employed as the main reactants to synthesize the triazophos hapten 6- [ethoxy （1-phenyl-1H-1,2,4-triazol-3-yloxy） phospho- rothioy-laminoJ hexanoic acid, the product were confirmed by MS and ^1H-NMR. The result showed that the hapten synthesis strategies and condition is suitable and will be contributed to antibody preparation.
出处
《中国食品学报》
EI
CAS
CSCD
2006年第1期20-24,共5页
Journal of Chinese Institute Of Food Science and Technology
基金
国家自然科学基金项目(No.20477012)
广东省自然科学基金重点项目(No.036842)
关键词
三唑磷
芈抗原
合成
鉴定
Triazophos Hapten Synthesis Identification
