摘要
目的探讨宫颈分泌物中胰岛素样生长因子结合蛋白-1(IGFBP-1)的检测在判断早产的价值。方法选择89例先兆早产孕妇和90例正常孕妇,应用免疫层析法对其宫颈分泌物进行胰岛素样生长因子结合蛋白-1(IGFBP-1)的检测。结果先兆早产组IGFBP-1的阳性率是69.7%,正常妊娠组IGFBP-1的阳性率是10.0%,两组结果比较,差异有显著性意义(P<0.05)。先兆早产IGFBP-1的阳性发生早产率是90.3%。结论检测IGFBP-1可以作为预测早产的客观指标,对临床有较大应用价值。
Objective To study the value of insulin like growth factor binding proterin_l （IGFBP_1） in cervicovaginal secretions for the diagnosis of premature labor . Methods 89 cases of reptured amniotic membranes and 90 casesof term pregnancy tooke part in our prospective study. IGFBP_1 in cervincovaginal secretions was measured by immunochromaatography methods. Rusults The positive rate of IGFBP_1 was 69.7% in the threatened premature labor group and 10,0% in the normal group, with significant differnce between two group （P〈0.05）. The premature labor rate in the threatened premature labor group with positive reaction of IGFBP_1 was 90.3%. Conclusion Detecting the phosphorylated is oforms of IGFBP_1 can be used as a objective index for predicting premature labor.
出处
《国际医药卫生导报》
2006年第4期20-21,共2页
International Medicine and Health Guidance News
关键词
胰岛素样生长因子结合蛋白-1
早产
Insulin-like growth factor binding protein-1 Premature labor
