摘要
采用顶空—固相微萃取—气相色谱联用技术测定了氨苄西林钠中丙酮和异丙醇残留量。使用100μmPDMS萃取头,顶空平衡温度为60℃,萃取时间为40 min,2m×3 mm(i.d.)不锈钢色谱柱、内填充10%丁二酸乙二醇聚酯/202酸洗红色担体。外标法定量,丙酮测定结果的相对标准偏差(RSD)为0.43%,在0.1μg/g^20μg/g范围时,色谱峰面积与质量浓度之间呈良好线性关系,相关系数(R2)为0.979 9,回收率为97.8%~103%;异丙醇测定结果的相对标准偏差(RSD)为0.88%,在0.2μg/g^20μg/g范围时,色谱峰面积与质量浓度之间呈良好线性关系,相关系数(R2)为0.980 2,回收率为95.7%~101%。
In this paper, headspece-SPME-gaschromatography was used to determine residual acetone and isopropenol in ampicillin sodium. Polydimethysiloxane（100μn） used as adsorbent. The headspace bottle was put in a water bath at 60℃ .Absorption time was 40 min.2 m × 3 mmi. d. GC colum packed with 10% polyethylene glycol succinate/202 pickling red support used to separat acetone and isopropanol. Extenal standard method was used for quantitation. There were all good linear relationships between the concentratiOn and the relative peak areas of acetone and isopropanl. Foracetone, in the range of 0.13 μg/g ～ 20 μg/g, the corrlation coefficient（ R^2） was 0.9799, the relative standard deviation was 0.43 and the recoveries were 97.8 % ～ 103 %. For isopropanol, in the range of 0.21μg/g ～ 20μg/g, the corrlation coefficient（ R^2） was 0.9799,the relatiVe standard deviation was 0.88 and the recoveries were 95.7% ～ 101%.
出处
《化工时刊》
CAS
2006年第3期35-37,共3页
Chemical Industry Times
