摘要
综述了甘草中有效成分甘草酸的提取、纯化和测定方法的研究概况。稀醇溶液对甘草酸的提取效果较好,添加稀氨水后可提高甘草酸的提取收率;超声波强化或微波辅助提取可提高甘草酸的提取效率并节约提取溶剂和提取时间,CO2超临界流体法无毒、高效且不需加热即可将甘草酸与溶质分离开来;TLC,HPLC,CE方法可实现甘草酸及甘草次酸含量的快速、准确测定。
Extraction, purification and determination methods of glycyrrhizic acid in Licorice are surveyed in this paper. The extracting efficiency of dilute ethanol solvent for glycyrrhizic acid is higher than water extraction, and ammonia appended to ethanol solution can increase the effect of extraction. Ultrasound method,microwave-assisted method and supercritical CO2 fluid extraction are more effective than the conventional techniques,due to the short extraction time, low consumption of solution and energy. The modem analytical methods such as TIEs, HPLC and CE can determine the content of glycyrrhizic acid rapidly and exactly.
出处
《中国中药杂志》
CAS
CSCD
北大核心
2006年第5期357-360,共4页
China Journal of Chinese Materia Medica
关键词
甘草
甘草酸
提取
测定
licorice
glycyrrhizic acid
extraction
determination
