摘要
目的了解长期改水预防地方性氟中毒的效果及病区居民骨关节X线表现。方法分析2例改水前氟骨症患者X线片结果。选择有或无骨关节症状、体征居民28人进行前臂、小腿和骨盆X线检查。统计氟骨症和其他疾病检出率、氟骨症骨炎节X线表现;同时调查受检者氟斑牙、骨关节症状、体征检出率,测定尿氟水平。结果 2例改水前患者1例为Ⅲ度骨硬化,另1例为Ⅲ度骨软化。被检查的28人中,15人(53．6％)有异常X线改变,其中氟骨症6人(21．4％),均为改水前居住当地者,最重改变为Ⅱ度。在各种X线征象中,关节改变出现频率最高,骨质改变次之,骨周改变较少。28人的尿氟均值为0．99 mg／L。6名氟骨症患者尿氟为1．40 mg／L。结论阻断高氟摄入40年后,高氟区居民和氟骨症患者体内大量氟化物被排除,严重的氟骨症已消失。但骨关节症状、体征检出率仍然较高,氟骨症患者依然存在。改水使一些患者康复是可能的,但使所有氟骨症患者完全康复是困难的。
Objective To understand the effect to control endemic fluorosis,and the X-ray signs of bone and joint among residents of the endemic area long after improvement of water. Methods The X-ray signs of 2 cases of skeletal fluorosis before improving water were analyzed. X-ray photographs of pelvis,forearm and shank were taken among residents with or without symptoms of bone and joint among 28 residents. The rate of skeletal fluorosis,mottled dental,clinical symptoms were investigated,and the urinary fluoride content was measured. Results X-ray signs of 2 patients before improving water clearly showed Ⅲ grade fluorosis, with one （male） exhibiting osteosclerosis and other（female） osteomalacia. 15 among 28 residents had abnormal X-ray signs（53.6%）, there was 6 cases skeletal fluorosis （21.4%）,and Ⅲ stage fluorosis had dropped. Changes of joint were the most frequently seen X-ray signs, bone changes ranked the second, periost the last. Urinary fluoride content was 0.99 mg/L among 28 residents,and was 1.40 mg/L in 6 cases skeletal fluorosis. Conclusions 40 years after improving water, a large quantity of fluoride has been excreted from body, and serious skeletal fluorosis has disappeared; however, symptoms of bone and joint and X-ray signs are still detectable and skeletal fluorosis exists among the residents. It is possible that a number of patients restore to health through improving water,but complete recovery for all patients is difficult.
出处
《中国地方病学杂志》
CAS
CSCD
北大核心
2006年第2期192-195,共4页
Chinese Jouranl of Endemiology
关键词
氟化物中毒
改水
骨
X线
康复
Fluoride poisoning
Improving water
Bone
X-rays
Rehabilitation
