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缝隙连接与心房颤动的折返机制 被引量：3

Relationship Between Gap Junction and Reentrant Mechanism of Atrial Fibrillation
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摘要 缝隙连接(GJ)由缝隙连接蛋白(Cx)构成,GJ作为细胞间的一种特殊通道介导着细胞间电和化学信号的传递,在维持电和机械耦联的正常进行以确保心肌协调收缩方面起着重要作用。GJ重构易致微折返形成,因而心房颤动容易产生和维持。 Gap junction （G J） composed of connexins, which is a special membrane pathway, mediates the transmission of electrical and chemical signals. It plays an important role in maintaining normal clectromechanieal coupling for synehronizod contraction of myocardium. The remodeling of GJ is prone to form microreentry,which tends to cause and maintain the atrial fibrillation.
作者 成永霞 钟国强
机构地区 广西医科大学第一附属医院心内科
出处 《医学综述》 2006年第6期335-336,共2页 Medical Recapitulate
关键词 心房颤动 缝隙连接 缝隙连接蛋白 折返 Atrial fibrillation Gap junction Connexin Reentrant
分类号 R541.75 [医药卫生—心血管疾病]
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参考文献18

  • 1钟国强,黄从新,刘唐威,Mantel PL,Moreno AP.异型缝隙连接通道和磷酸化对心脏缝隙连接的调变[J].中华心律失常学杂志,2003,7(4):229-233. 被引量：9
  • 2钟国强,黄从新,刘唐威,Patricia Lynn Mantel,Alonso P.Moreno.异型缝隙连接通道和磷酸化对心脏细胞通讯的调节作用[J].中国心脏起搏与心电生理杂志,2003,17(3):195-199. 被引量：4
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二级参考文献48

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医学综述
2006年 第6期

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