摘要
组织工程包括种子细胞、生物材料和组织构建三部分。种子细胞的来源和种类是心肌组织工程的关键环节,目前研究较多的主要有胎幼心肌细胞、心脏自体细胞和全、多能干细胞等。生物材料是细胞附着的基本框架和代谢场所,直接影响所构成的组织形态和功能。生物反应器系统使体外构建理想的工程化心肌组织成为可能。本文介绍近年来心肌组织工程在上述三方面的研究进展。
Tissue engineering includes seeded cells, biomaterial and tissue construct. The resource and category of seeded cells are the key points of myocardiac tissue engineering. At present, researches lie mainly in the fetal and neonatal myocardiac cells, host heart cells, totipotencial and pluripotencial cells and so on. The biomaterial on which the seeded cells could be grown is the basic framework and metabolism locus, which can influence directly the shape and function of the constructed tissue. The bioreactor makes the engineered myocardiac tissue in vitro possibly. This article introduces the progress of myocardiac tissue engineering in the above mentioned in recent few years.
出处
《上海交通大学学报（医学版）》
CAS
CSCD
北大核心
2006年第1期96-99,共4页
Journal of Shanghai Jiao tong University:Medical Science
