摘要
本文介绍了有机锗(Ge132)调节IFN—Mφ对带瘤动物的抑瘤效应,及Ge132对氨基甲酸乙酯诱发性肿瘤的影响。结果表明:(一)Ge_(132)能诱生γ—IFN激活巨噬细胞,发挥对IFN—Mφ的正性调节作用,实现了对肿瘤细胞的攻击。(二)Ge_(132)可明显抑制氨基甲酸乙酯诱发性小鼠肺腺瘤的发生。提示Ge_(132)是一种有前途的生物反应调整剂。
The biological responce modification effect of organic germanium Ge132 was studied. The results showed that the Gel32 has immunopotentiating effects, inducing the host r-IFN secretion, which activates the phagocytes to attack S-180 tumor cells. On the other hand, it reduced the incibcnced of Urethane induced lung adenoma in mice. So the organic Germanium (Ge132) is regarded as an useful BRMs.
出处
《癌症》
SCIE
CAS
CSCD
北大核心
1990年第6期478-480,共3页
Chinese Journal of Cancer
基金
国家自然科学基金
