期刊文献+
任意字段
题名或关键词
题名
关键词
文摘
作者
第一作者
机构
刊名
分类号
参考文献
作者简介
基金资助
栏目信息

重型颅脑损伤病人颅内压变化及纳洛酮的治疗作用 被引量：6

Naloxone's effect on Pbt O_2,ICP and prognosis in patients with severe head injure
暂未订购
导出
摘要 目的观察重型颅脑损伤患者颅内压变化及大剂量纳洛酮的治疗效果。方法选择重型脑损伤患者（GCS计分3—8分）82例。随机分治疗组42例，除采用临床综合治疗外并应用大剂量纳洛酮；对照组仅采用临床综合治疗，监测颅内压及常规临床监护，观察病人预后。结果重症颅脑外伤病人颅内压增高明显，颅内压．急剧升高与死亡率明显相关。纳洛酮治疗组颅内压明显低于对照组，预后较对照组好，并发症少。结论重症颅脑外伤颅内压水平与病人预后明显相关。大剂量纳洛酮能够改善重症颅脑损伤引起的脑水肿、高颅压，进而改善脑组织缺氧，改善病人预后。 Objective To investigate the change of intracranial pressure（ICP）level and prognosis in patients with severe head injure and naloxone＇s effect. Methods Eighty - two patients with severe head injure（ GCS 〈 8 ） were divided into control group（n = 40）and treatment group（ n = 42）.The patients in treatment group were given naloxone in addition to the common treament received by those in control group. ICP were monitord. Results ICP in treatment group were obviously lower than that in control group. Prognosis of the treatment group were much better. ConclusionNaloxone can improve the prognosis of severe head injure.
作者 陈大庆 张志军
机构地区 温州医学院附属第二医院神经外科 吉林大学附属第一医院血液内科
出处 《中国实用神经疾病杂志》 2006年第1期43-44,共2页 Chinese Journal of Practical Nervous Diseases
关键词 颅内压 重型颅脑损伤 纳洛酮 Severe head injure CP Naloxonel
分类号 R651.15 [医药卫生—外科学]
  • 相关文献

参考文献5

  • 1[1]Kiening KL,Hartl R,Unterberg AW,et al.Brain tissue PO2 monitoring in comatose patients implication for therapy[J].Neurol Res,2000,19(3):233～240
  • 2许璟,陈大庆,尹波,张弩,牟朝晖.重型颅脑损伤后脑组织氧分压和颅内压监测及其临床意义[J].浙江创伤外科,2002,7(4):211-213. 被引量：5
  • 3[3]Diungs J,Jager A,Meixensberger J,et al.Brain tissue PO2 and outcome after severe head injury[J].Neurol Res,2002,27(2):87～134
  • 4[4]Hoffman WE,Charbel FT,Edelman G,et al.Brain tissue oxgen pressure,carbon dioxide pressure,and PH during hypothermic circulatory arrest[J].Surg Neurol,1999,46(1):75～79
  • 5[5]Hoffman WE,Charbeel FT,Abood C,et al.Regional ischemia during cerebral bypass sur gery[J].Surg Neurol,2000,47(4):455～459

二级参考文献9

  • 1Kiening KL, Hartl R, Unterberg AW, et al. Brain tissue pO2-monitoring in comatose patients: implications for therapy. Neurol Res, 1997, 19(3): 233-240.
  • 2Bouma GJ, Muizelaar JP, Choi SC, et al. Cerebral circulation and metabolism after severe traumatic brain injury: the elusive role of ischemia. J Neurosurg, 1991, 75(5): 685-693.
  • 3Kiening KL, Unterberg AW, Bardt TF, et al. Monitoring of cerebral oxygenation in patients with severe head injuries: brain tissue pO2 versus jugular vein oxygen saturation. J Neurosurg,1996, 85(5): 751-757.
  • 4van Santbrink H, Maas AI, Avezaat CJ. Continuous monitoring of partial pressure of brain tissue oxygen in patients with severe head injury. Neurosurgery, 1996, 38(1): 21-31.
  • 5O'Sullivan MG, Statham PF, Jones PA, et al. Role of intracranial pressure monitoring in severely head-injured patients without signs of intracranial hypertension on initial computerized tomography. J Neurosurg, 1994, 80(1):46-50.
  • 6Dings J, Jager A, Meixensberger J, et al. Brain tissue pO2 and outcome after severe head injury. Neurol Res,1998, 20: S71-75.
  • 7Kett-White R, Hutchinson PJ, Czosnyka M, et al. Multi-modal monitoring of acute brain injury. Adv Tech Stand Neurosurg,2002, 27: 87-134.
  • 8Menzel M, Rieger A, Roth S, et al. Comparison between continuous brain tissue pO2, pCO2, pH, and temperature and simultaneous cerebrovenous measurement using a multisensor probe in a porcine intracranial pressure model. J Neurotrauma,1998, 15(4):265-276.
  • 9Dings J, Meixensberger J, Amschler J, et al. Brain tissue pO2 in relation to cerebral perfusion pressure, TCD findings and TCDCO2-reactivity after severe head injury. Acta Neurochir (Wien) ,1996, 138(4):425-434.

共引文献4

同被引文献94

引证文献6

二级引证文献38

中国实用神经疾病杂志
2006年 第1期

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部