摘要
目的:探讨葡萄糖6磷酸脱氢酶缺乏程度与患儿高胆红素血症发生率的关系。方法:对近5年来产科分娩的足月健康新生儿脐血进行G6PD定量测定,对G6PD活性缺乏的患儿,按酶活性缺乏程度分组调查其高胆红素血症的发生率。结果:①G6PD活性缺乏的患儿与对照组比较,高胆红素血症发生率和血清胆红素测定水平有极显著性差异(P<0.01)。②患儿组中,G6PD活性缺乏程度不同的3组患儿高胆红素血症发生率有显著性差异(P<0.05)。结论:G6PD活性缺乏程度与患儿高胆红素血症的发生率有显著的相关性。
Objective： To evaluate the relationship between the incidence of hyperbilirubinemia and the degree of the G6PD （ glucose - 6 phosphate dehydrogenate） deficiency. Methods： The G6PD levels in umbilical blood of the mature healthy neonates delivered in the 5 recent years in the obstetrical department were determined to study the incidence of hyperbilirubinemia according to the deficiency extent of the enzymatic activity in the G6PD deficiency patient - infants. Results：①There were greatly significant differences in incidence of hyperbilirubinemia and the level of serum bilirubin between hospitalized children With G6PD deficiency and control group （P 〈 0. 01 ） . ②There were significant differences in the incidence of hyperbilirubinemia among three different G6PD deficiency groups （P 〈 0. 05 ） . Conclusion： There is a remarkable relationship between the degree of the G6PD deficiency and the incidence of hyperbilirubinemia.
出处
《中国妇幼保健》
CAS
北大核心
2005年第24期3284-3285,共2页
Maternal and Child Health Care of China
关键词
葡萄糖6磷酸脱氢酶
缺乏程度
高胆红素血症
发生率
Glucose - 6 phosphate dehydrogenate
Deficiency extent
Hyperbilirubinemia
Incidence
