摘要
目的观察茶色素对高血压患者脂质过氧化反应和载脂蛋白的影响。方法 22例患者服茶色素3粒/d 连续4w,在服药前后分别测定 SOD、LPO、Apo A、B。结果高血压患者 SOD活力和 LPO 含量与正常人比较有明显差异(87.45±21.24和5.87±1.38对102.8±12.26 nU/ml 和3.18±0.98 nmol/L,P<0.05～0.01),服用茶色紊后患者 SOD 活力升高到101.04±18.07 nU/ml,LPO 含量降低至4.07±0.93(P<0.01),而茶色素对血压和 Apo A、B 无明显影响。结论茶色素具有一定的抗脂质过氧化作用,能减轻高血压患者的代谢失衡。
Aim To investigate the effect of tea pigment on lipid peroxidation and Apo A,B in pa- tients with essential hypertension.Method Twen- ty two patients were administrated tea pigment 3 cap- sules daily for 4 weeks.SOD activity and LPO, ApoA,B and A/B contents were determined before and after administration.Results There were sig- nificant differences in SOD activity and LPO content between the patients and controls(87.45±21.24 and 5.87±1.38 vs 102.8±12.26 nU/ml and 3.18±0.98 nmol/L respectively,P<0.05～0.01).After admin- istration of tea pigment the SOD activity increased to 101.04±18.07 nU/ml and LPO content decreased to 4.07±0.93 nmol/L(P<0.01).However,tea pig- ment had no significant effects on blood pressure and APO A/B.Conclusion Tea pigment has the effect of anti-peroxidation and might attenuate the metabol- ic imbalance.
出处
《高血压杂志》
CSCD
1996年第2期142-143,共2页
Chinese Journal of Hypertension
关键词
茶色素
高血压
超氧化物
歧化酶
过氧化脂质
tea pigment
essential hypertension
lipid peroxidation
superoxide dismutase
