摘要
利用吡拉西坦的乙酰胺基与羟胺反应生成N-羟胺基酰胺,用铁离子显色后,在500nm波长处进行分光光度测定。平均回收率为99.49%,RSD为0.26%(n=5)。方法简便,快速。
The acetamido group of piracetam reacts with hydroxylamine to form N-hydroxyamino-amide which gives color reaction with Fe+++ and can be used for determination of piracetam and its tablets by spectrophotometry at the wavelength of 500 nm. The average recovery was 99.49% (RSD= 0.26%) . This method is simple, accurate and rapid.
出处
《中国医药工业杂志》
CAS
CSCD
北大核心
1996年第3期125-127,共3页
Chinese Journal of Pharmaceuticals
关键词
吡拉西坦
片剂
分光光度法
piracetam, tablets, spectrophotometry, determination