期刊文献+

肌纤维母细胞与盆腔子宫内膜异位症的关系

Relationship between Myofibroblast and Pelvic Endometriosis
暂未订购
导出
摘要 目的观察盆腔异位子宫内膜中肌纤维母细胞(MFB)的表达。方法采用免疫组织化学方法对44例盆腔子宫内膜异位症手术切除组织行α-平滑肌肌动蛋白(-αSMA)染色,4例异位子宫内膜及2例在位子宫内膜行透射电子显微镜检查。结果-αSMA异位子宫内膜86.4%(38/44)MFB阳性,同一病人在位子宫内膜18.2%(8/44)MFB阳性,电镜证实异位子宫内膜、在位子宫内膜中存在MFB。结论MFB在盆腔子宫内膜异位症中起一定的作用。 Objective To observe the expression of myofibroblast in ectopic endometrium in the pelvis. Methods The expression of α-smooth muscle actin(a-SMA) α-SMA by immunohistochemistry was detected in 44 cases of pelvic endometriosis. Four cases of ectopic endometrium and two cases of eutopic endometrium were examined by transmission electron microscope. Results The positive expression of α-SMA in ectopic endometrium was 86.4% (38/44) and 18.2% (8/44) in eutopic endometrium. Conclusion Myofibroblast existed in ectopic and eutopic endometrium was identified with transmission electron microscope. Myofibroblast plays a certain role in the pathogenesis of pelvic endometriosis.
出处 《福建医科大学学报》 2005年第4期383-385,共3页 Journal of Fujian Medical University
关键词 成纤维细胞 子宫内膜异位症 肌动蛋白类 检查 电子 扫描透射 fibroblast endometriosis actin microscopy, electron, scanning tramsmission
  • 相关文献

参考文献9

  • 1郎景和,冷金花,赵栋,钟森.第八届国际子宫内膜异位症学术会议纪要[J].中华妇产科杂志,2002,37(10):638-640. 被引量:59
  • 2Gabbiani G, Ryan GB, Majno G. Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction [J]. Experientia , 1971,27(5) :549-550.
  • 3赖日权 熊敏.纤维性肿瘤和瘤样病变[A].见:范钦和.软组织病理学[M].南昌:江西科学技术出版社,2003.38-39.
  • 4Darby I, Skalli O, Gabbiani G. e-smooth muscle actin is transiently expressed by myofibroblasts during experimental wound healing[J]. Lab Invest, 1990, 63:21.
  • 5Boris H, Giuseppe C, James J, et al. Alpha-smooth muscle actin expression upregulates fibroblast contractile activity[J]. Mol Biol Cell,2001,12(9):2730-2741.
  • 6刘能保 李肇春.固有结缔组织[A].见:成令忠.现代组织学[M].上海:上海科学技术文献出版社,2003.84-185.
  • 7陈光勇,张长淮,陈煜.肝纤维化中肝星状细胞和肌纤维母细胞的形态学观察[J].临床和实验医学杂志,2002,1(3):153-156. 被引量:1
  • 8王军,邵传森,程晓霞,王永钧.α平滑肌肌动蛋白和转化生长因子β_1在小管间质纤维化模型大鼠肾组织中的表达[J].浙江医学,2002,24(12):726-727. 被引量:8
  • 9Lokman K, Erhan Y, Omer A, et al. Soft tissue contractures in clubfoot: An immunohistochemical study[J]. Arthrop Arthrosco Surg, 2004,15(1) :26-30.

二级参考文献9

  • 1Fan JM, Ng YY, Hill PA, et al. Tansforming growth factor β1 regulates tubular epithelial-myofibroblast transdifferentitation in vivo. Kidney Int, 1999, 56(4): 1455.
  • 2Jinde K, Nikolic-Paterson DJ, Huang XR, et al. Tubular phenotypic change in progressive tubulointerstitial fibrosis in human glomerulonephrosis. Am J Kid Dis, 2001,38(4): 761.
  • 3Kaneto H, Morrissey J, Klahr S. Increased expression of TGF-β1 Mrna in the obstructed kidney of rats with unilateral ureteral ligation. Kidney Int, 1993,44(3): 311.
  • 4Ishidoya S, Morrissey J, McCracken R, et al. Angiotensin Ⅱ receptor antagonist ameliorates renal tubulointerstitial fibrosis caused by unilateral ureteral obstruction. Kidney Int, 1995,47(5): 1285.
  • 5Edoardo Giannini,Federica Botta,Alberto Fasoli,Paola Ceppa,Domenico Risso,Pasquale Bruno Lantieri,Guido Celle,Roberto Testa. Progressive Liver Functional Impairment Is Associated with an Increase in AST/ALT Ratio[J] 1999,Digestive Diseases and Sciences(6):1249~1253
  • 6Volker Arndt,Hermann Brenner,Dietrich Rothenbacher,Bernd Zschenderlein,Eckart Fraisse,Theodor M. Fliedner. Elevated liver enzyme activity in construction workers: prevalence and impact on early retirement and all-cause mortality[J] 1998,International Archives of Occupational and Environmental Health(6):405~412
  • 7李缨,翟为溶,张清波.慢性肝炎病理分类与临床的关系[J].肝脏,2000,5(1):2-4. 被引量:15
  • 8病毒性肝炎防治方案[J].中华传染病杂志,2001,19(1):56-62. 被引量:1827
  • 9程晓霞,王军,周大伟,陈红宇,胡云琴.伊贝沙坦对大鼠单侧输尿管结扎致肾损伤的保护作用[J].中国中西医结合肾病杂志,2002,3(10):593-594. 被引量:2

共引文献66

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部