摘要
目的探讨原发性乳腺恶性淋巴瘤的诊断与治疗。方法回顾性分析我院1992～2004年5例原发性乳腺恶性淋巴瘤的临床资料。5例均为术后组织学病理诊断。4例行乳腺癌改良根治术,1例行乳房单纯切除术。5例均行化疗及放疗。结果乳腺癌改良根治术手术时间60～120min,平均80min;乳房单纯切除术加乳腔镜腋窝淋巴结清扫术手术时间75min。术中出血量150～250ml,平均200ml。术后病理组织诊断均为弥漫性非霍奇金氏淋巴瘤,为B细胞来源。且均有腋窝淋巴结转移。全组病例随访6个月～12年,平均4.5年。2例II期,均死于肿瘤多器官转移;3例I期,肿瘤无复发。结论原发性乳腺恶性淋巴瘤无明显特异性表现,术前诊断困难。钼靶X线照相,对诊断有帮助。治疗可选择手术、放疗、化疗或单纯给予化疗和放疗。
Objective To discuss the diagnosis and treatment of primary malignant lymphoma of the breast. Methods A retrospective review of clinical records of 5 cases of primary malignant breast lymphoma from 1992 to 2004 was made. All the 5 cases were confirmatively diagnosed by pathological examinations after the surgery. Four cases were given a modified radical mastectomy and 1 case received a simple mastectomy. Adjuvant chemotherapy and radiotherapy was employecl in all. Results The operation time of modified radical mastectomy was 60 - 120 min （ mean, 80 min） , and the operation time of simple mastectomy with axillary lymph node dissection was 75 min. The intraoperative blood loss was 150 -250 ml （mean, 200 ml）. Postoperative pathological examinations showed aggressive subtypes of B-cell non-Hodgkin lymphoma in all the cases, with axillary lymph node involvement. All the patients were followed for 0. 5 - 12 years （ mean, 4.5 years）. Two patients with stage Ⅱ lymphoma died of multiple organ metastasis and 3 patients with stage Ⅰ lymphoma were free of recurrence. Conclusions Primary malignant breast lymphoma is marked by non - specific clinical manifestations and is difficult to clarify the diagnosis before operation. Molybdenum target mammography is helpful to the diagnosis. Proper remedy at our disposal is the combination of surgical operation, radiation therapy and chemotherapy, or chemotherapy or radiation therapy alone.
出处
《中国微创外科杂志》
CSCD
2005年第11期907-908,共2页
Chinese Journal of Minimally Invasive Surgery
