摘要
目的：总结原发性乳腺淋巴瘤（PBL）的临床特征并探讨其预后因素。方法：回顾性分析15例PBL的临床资料并复习同期国内文献共134例报告，运用SPSS软件包分析其预后因素。结果：15例PBL均为术后明确诊断。中位年龄42岁，全部为NHL，其中DLCL型占53．33％，10例右乳首发，文献统计分析显示右乳多发（59％，且乳房肿块大小和治疗模式是重要的预后因素，而与年龄、左或右乳首发分组其生存期无显著差别。结论：PBL以NHL占绝大多数，右乳首发多见，术前诊断困难，治疗宜选择手术联合放疗或（和）化疗的综合治疗模式。
Objective To study the clinical features and significant prognostic factors of primary breast lymphoma PBL． Methods A retrospective clinical analysis of 15 patients with PBL and a statistical analysis of 134 cases with PBL were performed． Results All 15 patients but one were female with 42 in median age． None was diagnosed with PBL preoperatively． Pathological study showed that all cases were non－Hodgkin＇s lymphoma with DLCL type in working formulation 53．33％． The right breast was affected in 10 the left in 4 and both in one． A statistical analysis showed that the size of tumors at diagnosis and treatment pattern single or multi－modality were significant prognostic factors in predicting the survival time but the location of the tumor at initial presentation and age of the patients were not． Conclusion Most PBLs are NHL． The right breast is more frequently involved． The correct diagnosis depends mostly on postoperative pathology． The size of the tumor and treatment modality are significantly prognostic factors．
出处
《中国肿瘤临床》
CAS
CSCD
北大核心
2001年第7期501-503,513,共4页
Chinese Journal of Clinical Oncology
