摘要
目的探讨原发性乳腺淋巴瘤（PBL）的临床病理特点。方法回顾性分析36例PBL患者的临床资料。结果36例PBL患者中，Ⅰa期16例，Ⅱa期14例，Ⅱb期2例，IVb期4例，患者均行手术治疗加化疗，其中20例加行放疗。33例（91．7％）随访3～193个月，随访期间死亡12例，其中死于脑转移2例，骨髓转移5例，肝、肺广泛转移5例。存活21例中，最长者192个月，总生存时间3～192个月，中位生存时间43．5个月。全组3年和5年生存率分别为70.1％和49．0％。结论PBL中以B细胞型NHL常见，诊断主要依据术后的常规病理和免疫组化检查，一般采用手术、化疗及放疗等综合治疗。
Objective To explore the clinico- pathological characteristics of primary breast lymphoma （ PBL ）. Methods The clinical data of 36 cases of PBL were analyzed retrospectively. Results Among the 36 cases of PBL, 16 patients presented with stage Ⅰ a disease, 14 patients with stage IIa disease, 2 patients with stage Ⅱb disease, and 4 patients with stage Ⅳ. All of the patients underwent surgery and chemotherapy, and 20 cases had radiotherapy. Thirty three patients （91.7%） were followed up for 3 - 193 months, during which time, 12 patients died, including 2 patients died of brain metastases, five patients died of bone metastasis, and five patients died of diffuse hepatic and pulmonary metastasis. In the 21 surviving patients, the survival time was 3 - 192 months, and the median survival time was 43.5 months. The overall 3-and 5-year survival rate was 70. 1% and 49.0% , respectively. Conclusions Most PBL are NHL. PBL is diagnosed basically by methods of pathology and immunohistochemistry, and operation combined with chemotherapy and/or radiotherapy is the best treatment method.
出处
《中国普通外科杂志》
CAS
CSCD
2008年第5期433-435,共3页
China Journal of General Surgery
