摘要
观察吉西他滨联合奥沙利铂治疗老年晚期非小细胞肺癌(non-small cell lung cancer,NSCLC)的近期疗效及毒副反应.初治的Ⅲ～Ⅳ期老年NSCLC 22例,以21 d为1个周期,吉西他滨1000 mg/m2,静脉滴入,d1、d8;奥沙利铂100mg/m2,静脉滴入,d1.连用2个周期后评价疗效.全组22例均可评价,有效率为40.9%(9/22),毒副反应主要为骨髓抑制及外周神经感觉异常.初步研究结果提示,吉西他滨联合奥沙利铂治疗老年晚期NSCLC有一定的疗效,毒性较小可以耐受.
To evaluate the efficacy and toxicity of gemcitabin and oxaliplatin in the treatment of elderly patients with advanced non-small cell lung cancer, Selecting 22 previously untreated elderly patients with advanced non-small cell lung cancer, Domestic gemcitabine was given on d1 , d8 at a dose of 1 000 mg/m^2 and oxaliplatin at a dose of 100 mg/m^2 on d1. The chemotherapy was repeated every 21 days with two cycles. The response rate was 40.9^（9/22）. The side effects were myelosuppression and peripheral sensory neuropathy. Gemcitabin combined with oxaliplatin treating non-small cell lung in elderly people has some effect,and the toxiciey can be well tolerated.
出处
《肿瘤防治杂志》
2005年第18期1415-1416,共2页
China Journal of Cancer Prevention and Treatment
关键词
吉西他滨
奥沙利铂
癌
非小细胞肺/药物疗法
药物疗法
联合
gemcitabin
oxaliplatin
carcinoma, non small cell lung/drug therapy
drug therapy, combination
