摘要
目的研究严重少精子或无精子症患者外周血中雄激素受体mRNA的表达。方法采用RT-PCR方法分别检测12例正常男性和31例严重少精子或无精子症患者外周血雄激素受体mRNA的表达。结果所有正常男性和20例严重少精子或无精子症患者外周血雄激素受体mRNA的表达阳性,11例严重少精子或无精子症患者表达阴性。结论雄激素受体异常可能是部分严重少精子或无精子症患者的病因。
Objective To investigate androgen receptor mRNA expression in severe oligozoospermia or azoospermia patients. Methods Androgen receptor mRNA espression was determined by PT-PCR in 12 healthy men and 31 severe oligozoospermia or azoospermia patients. Results All health men and 11 patients expressed androgen receptor mRNA positive, while I l patients expressed negative. Conclusion The abnormal of androgen receptor mRNA espression may be the aetiology of some severe oligozoospermia or azoospermia patients.
出处
《中国男科学杂志》
CAS
CSCD
2005年第5期29-30,共2页
Chinese Journal of Andrology
