摘要
【目的】观察高氧液早期治疗重型颅脑损伤的效果。【方法】选择伤后6 h内新入院重型颅脑损伤患者68例,随机分为高氧液治疗组(简称治疗组)与对照组,每组各34例,分析比较两组动脉血氧分压(PaO2)、颅内压(ICP)、格拉斯哥昏迷记分(GCS)等生理及神经功能指标变化情况。【结果】治疗组在输注高氧液后PaO2明显高于对照组,7 d后ICP明显低于对照组,两周后GCS明显高于对照组。【结论】重型颅脑损伤患者早期应用高氧液治疗能改善脑组织缺血、缺氧,降低颅内压,促进患者神志的恢复。
[Objective]To study the therapeutic effects of high-oxygen liquid used early in the treatment of severe brain injury. [Methods]Sixty-eight patients with severe brain injury were divided into two groups at random：①Treated group-34 patients without compound trauma were admitted 6 hours after brain injury. The high-oxygen liquid was administered by drop infusion （500ml i v. b, i. d. ） for two weeks.②Control group, 34 patients were not treated by high-oxygen liquid but hyperbaric oxygen served as controls. The change of physiological and neurofunctional markers in two groups were compared, including arterial blood oxygen pressure （PaO2）, intracranial pressure （ICP） and the Glasgow coma scale （GCS）, [Results]The PaO2 in treated group after infusion of high-oxygen liquid was significantly higher than that of control group; the GCS of the former after two weeks was also significantly higher than the latter, while elevated ICP in treated group was significantly lower than that of control group. [Conclusion]Early application of high-oxygen liquid therapy to severe brain injury can decrease brain anoxia and prevent brain edema from increasing of ICP. thus hasten the recovery of coma.
出处
《医学临床研究》
CAS
2005年第9期1252-1253,共2页
Journal of Clinical Research
