摘要
目的:探讨彩色多普勒超声(简称彩超)导向下多方法联合治疗中晚期肝癌的临床价值。方法:在彩超引导下对治疗组117例中晚期肝癌患者行多电极射频治疗(RF)+无水乙醇瘤内注入(PEI)+门静脉化疗栓塞(SPVE)联合肝动脉化疗栓塞(TACE)治疗,观察并比较与对照组(110例单纯TACE的肝癌患者)治疗前后的声像图特征和临床疗效的关系。结果:治疗组术后3个月复查彩超,肿瘤缩小25.0%以上者为87.2%(104/117);肿瘤血供消失和减少率为88.0%(103/117);甲胎蛋白(AFP)转阴率为78.3%(54/69);1年和2年生存率分别为73.5%和62.4%,显著高于对照组的59.4%和32.6%。结论:多方法联合治疗中晚期肝癌是一种有效的治疗方法,彩超为指导治疗、动态监测和判断疗效提供依据。
Objective： To explore the value of combined treatment of advanced hepatic carcinoma. Methods ：117 cases with advanced hepatic carcinoma underwent a combined treatment by radio frequency ablation （ RF）, percutaneous ethanol injecton （ PEI ）, transcatheter hepatic arterial chemoembolization （ TACE） and transultrasonic portal vein chemoembolization （ SPVE ）. The comparison was made between this treatment and that of TACE alone in terms of size of tumor , changes of blood supply and clinical effects before and after each of these two treatments. Results： After three months, Uhrasonographic examination showed that the tumor size decreased by 25.0% was 87.2%. The disappearing rate and decreasing rate of blood supply of tumor was 88.0% ; AFP turning-negative rate was 78.3%. The follow-up survey showed that one-year and two-year survival rates for combined therapy were 73.5% and 62.4% respectively , significantly higher than that for the control TACE group 59.4% and 32.6%. Conclusion ： The combined treatments are effective ways for carcinoma treatment. Color Doppler imaging is important to guide and assess the treatment.
出处
《医学研究生学报》
CAS
2005年第9期800-801,共2页
Journal of Medical Postgraduates
基金
全军科研基金面上项目基金资助(批准号:98M032)
关键词
彩色多普勒超声
肝癌
联合治疗
Color doppler sonography
Hepatic carcinoma
Combined treatment
