摘要
目的:建立舒胸微丸中三种有效成分阿魏酸、川芎嗪和红花黄色素的含量测定方法。方法:采用 UV-Vis法测定红花黄色素的含量,HPLC 法测定阿魏酸与川芎嗪的含量。结果:阿魏酸与川芎嗪在1μg·mL^(-1)-150μg·mL^(-1)范围内线性关系良好,分别为0.9996和O.9998,平均回收率分别为96.3%(RSD=3.0%)和93.9%(RSD=2.3%);红花黄色素在1μpg·mL^(-1)—120μg·ml^(-1)范围内线性关系良好,r 为0.9999,平均回收率为101.1%(RSD=2.4%)。结论:本文所采用的含量测定方法准确,简便,灵敏可靠。
Objective： To develop a method to determine of the contents of Ferulic Acid, Tetramethylpyrazine and safflower yellow in Shuxiong pellets. Methods： The HPLC method was performed to determine the content of Fetulic Acid and Tetramethylprazine, and the UV- Vis method was used to assay the contents of safflower yellow in shuxiong pellets. Results： A good linearity was obtained within the range of 1μg·ml^-1- 150μg·mL^-1 for Ferulic Acid and Tetramethylprazine （r= 0.9996 and 0.9998, respectively）, and 10 μg·mL^-1-120μg·mL^-1 for safflower yellow （r= 0.9999）. The average recoveries of Ferulic Acid, Tetra methylprazine and safflower yellow were 96.3 （RSD=3.0%）, 93.9（RSD=2.3%） and 101.0% （RSD=2.4%）, respectively. Conclusion： The methods of determination of the three components in Shuxiong Pellet were simple, rapid, sensitive and accurate.
出处
《黑龙江医药》
CAS
2005年第4期241-244,共4页
Heilongjiang Medicine journal
