摘要
目的:早期类风湿性关节炎临床的症状不明显,因此临床对早期类风湿性关节炎的诊断有很多不便。近年来许多文献报道对类风湿性关节炎的实验诊断又有新的认识。敏感性高,特异性强的诊断方法对临床早期诊断治疗有重要意义。应用计算机检索Pubmed数据库1998年1月-2005年5月的相关文章,检索词为“rheumatoidarthritisNOTtreatmentANDdiagnosis”限定语言种类为英语。同时计算机检索http://www.chkd.cnki.net,1998年-1月-2005年-5月,限定语言种类为中文,检索词“类风湿性关节炎”,二次检索词“诊断”。对资料进行初审,选取与类风湿性关节炎早期血清和影像学诊断研究进展相关的文章,并开始查找全文,选取最新进展性文章纳入研究。共收集到41篇英文全文,53篇中文全文,排除重复或类似的同一研究,14篇符合本研究要求。针对类风湿性关节炎早期血清和影像学诊断的问题,对所检索出的众多观点进行提炼综合。结论:炎症介质,自身抗体等血清及影像学检查是早期确诊类风湿性关节炎的重要手段,但目前还没有一种公认的早期RA诊断标准。
Objective ：There are not manifest appearances with RA early, so it is hard to diagnosis. For the past few years, many literatures have reported new recognitions on laboratory diagnosis of rheumatoid arthritis. Diagnostic method that is hightly sensitive and specific is importaint to diagnosis RA early. Data sources：Using the key terms“rheumatoid orthritis NOT treatment and dignosis”, we search Pubmed Datebase between January 1998 and May 2005 in English. At the same time, a search of the website http：// chkd. cnki. net for such articles was also conducted with the key words of “rheumatoid arthritis”between January 1998 and May 2005 in Chinese. Secondly did it with the key words“diagnosis”in Chinese. Study selection ：All articles were selected firstly, and those were relevant to progression of early diagnosis by blood serum and imaging technique of rheumatoid arthritis were collected. The full text was looked up and the latest evolutional articles were collected. Data extration ：A total of 41 English articles and 53 Chinese articles were colleted. After the exclution of repeated and similar studies, 15 articles were suited to our eriteria. Data synthesis ： Aiming at the applied problem of progression of early diagnosis by blood serum and imaging techique of rheumatoid arthritis, the viewpoint of collected articles were summarized. The ineternational successful experience was introduced emphatically, and the most hopeful outlook was suggested. Conclusion ： Blood serum and imaging technique, such as mediators of inflammation and autoantibody, are important methods in early diagnosis of rheumatoid arthritis, but as yet there is not an generally accepted criterion of early diagnoisis of rheumatoid arthritis.
出处
《辽宁中医学院学报》
2005年第5期511-512,共2页
Journal of Liaoning College of Traditional Chinese Medicine
关键词
血清
影像学
类风湿性关节炎
早期诊断
serum
imaging technique
rheumatoid arthritis
early diagnosis
