摘要
目的观察雷米芬太尼复合丙泊酚持续泵注麻醉用于上腹部手术时的循环变化及术后苏醒过程。方法60例择期上腹部手术患者,随机均分为芬太尼组(F组)、雷米芬太尼组(R组)和雷米芬太尼+硬膜外阻滞组(C组),观察术中循环功能、麻醉苏醒及停药后的不良反应。结果R组与C组在气管插管、切皮、麻醉维持期间平均动脉压(MAP)及心率(HR)显著低于F组,R组自主呼吸恢复时间(7·5±4·1)min,呼之睁眼时间(10·1±4·7)min,拔管时间(12·5±5·0)min,定向力恢复时间(14·3±6·5)min,均较F组短,苏醒期质量C组优于R组和F组。结论雷米芬太尼复合硬膜外阻滞用于上腹部手术麻醉时,术中循环稳定,术后苏醒迅速,加用硬膜外麻醉可提高雷米芬太尼术后恢复质量。
Objective To observe the circulatory changes and recovery from anesthesia in patients operated for upper abdominal surgery under anesthesia with ramifentanil and propofol. Method According to the anesthetic method used , 60 selective upper abdominal surgical patients were divided randomly into fentanyl group（F）, ramifentanil group（R）, and ramifentanil plus epidural block group （C） with 20 cases each. The circulatory changes, recovery of anesthesia and side effects were observed perianesthestically. Results MAP and HR in group R and C were significantly lower than those in group F during intubation, skin incision, and maintenance of anesthesia. After the completion of anesthesia, the time of spontaneous respiration reestablishment was （7.5 ± 4.1 ）min, of eye opening （10.1±4.7） min, of extubation （12.5±5.0） min, and of orientation （14.3±6.5） min in group R, which were all shorter than those in group F. The quality of anesthesia recovery was better in group C than that in group R and F. Conclusion Anesthesia with ramifentanil combined with epidural block has the advantages of stable circulatory function, quicker awakeness , and better quality of recovery.
出处
《江苏医药》
CAS
CSCD
北大核心
2005年第9期659-661,共3页
Jiangsu Medical Journal
