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心脏端粒酶的研究概况 被引量：1

Research of Cardiac Telomerase
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摘要 端粒长度、端粒酶活性在心血管疾病发生发展过程中的变化引起了心血管界的关注。现就端粒酶在正常心脏中的表达及活性的变化,端粒酶与心肌细胞损伤、冠状动脉粥样硬化、心力衰竭等心血管疾病之间的关系和检测心脏端粒长度和端粒酶活性的技术和方法作一综述。 It arouses attention in cardiovascular field that the changes of telomere length and telomerase activity during occurrence and development of cardiovascular diseases. The review summarized the changes of telomerase expression and activity in normal heart, the relation between telomerase and cardiovascular diseases such as injured myoeardium, coronal atherosclerosis, heart failure and so on, and the technologies and methods of measuring telomere length and telomerase activity in the heart.
作者 常连生 郭志坤
机构地区 新乡医学院心脏形态学研究室
出处 《心血管病学进展》 CAS 2005年第5期547-550,共4页 Advances in Cardiovascular Diseases
基金 河南省自然科学基金项目(412000900)
关键词 端粒 端粒酶 心血管疾病 心肌细胞损伤 冠状动脉粥样硬化 心力衰竭 Telomere Telomerase Cardiovascular diseases Injured myocardium Coronal atherosclerosis
分类号 R541 [医药卫生—心血管疾病]
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参考文献25

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二级参考文献37

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心血管病学进展
2005年 第5期

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