3Chong L, van Steensel B, Brocoli D, et al. A human telomeric protein[ J]. Science, 1995,270(5242) : 1663-1667.
4Bianchi A, Smith S, Chong L, et oal. TRFI is a dimer and bends teolmefic DNA[ J]. EMBO J, 1997,16(7) : 1785-1794.
5Bilaud T, Brun C, Ancelin K, et al. Telomeric localization of TRF2, a movel human telobox protein [ J ]. Nature Genet, 1997,17 (2) : 236-239.
6Nakamura TM, Cech TR. Reversing time origin of telomerase[ J]. Cell,1998.92(5) :587-590.
7Greider CW, Autexier C, Buchkovich T, et al. Telomerase biochemisty and regulaiton in cellular immortalization[ J]. Proc Am Assoc Cancer Res, 1995,36(7) :672-677.
8Kim NW, Piatszek MA, Prowse KR, et al. Specific association of human telomerase activity with immortal cells and cancer[ J]. Science, 1994,266(5190) :2011-2015.
10Maruyama Y, Hanai H, Fujita M, et al. Telomere length and telomerase activity in carcinogenesis of the stomach[ J]. Jpn J Clin Oncol, 1997,27(4) :216-220.
2Harley CB, Futcher AB, Greider CW. Telomeres shorten during aging of human fibroblasts[J], Nature, 1990,345: 458-- 460.
3Levy MZ, Allsopp RC, Further AB, et al.Telomere end replication problem and cell aging[J].J Mol Biol, 1992,225: 951-960.
4Matsutani N, Yokozaki H, Tahara E, etal. Expression of telomeric repeat binding factor 1 and 2 and TRF1-interacting nuclear protein 2 in human gastric carcinomas[J]. Int J Oncol,2001,19: 507-512.
5van den Brandt PA, Goldbohm RA. Nutrition in the prevention of gastrointestinal cancer[J]. Best Pract Res Clin Gastroenterol,2006,20: 589-603.
6Huang HY, Caballero B, Chana S, et al. Multivitamin/ mineral supplements and prevention of chronic disease [J]. Evid Rop Technol Assess (Full Rep), 2006, (139):1-117.
7Wei WQ, Abnet CC, Qiao YL, et al. Prospective study of serum selenium concentrations and esophageal and gastric cardia cancer, heart disease, stroke, and total death[J]. Am .J Clin Nutr, 2004, 79:80-85.
8Gu Y, Li H, Miki J, et al.Phenotypic characterization of telomerase-immortalized primary non-malignant and malignant tumor derived human prostate epithelial cell lines[J]. Fxp Cell Res, 2006,312: 831-843.
9Pantic M, Zimmermann S, El Daly H, et al. Telomere dysfunction and loss of p53 cooperate in defective mitotic segregation of chromosomes in cancer cells[J]. Oncogeno, 2006, 25: 4413-4420.
10He H, Xia HH, Wang JD, et al. Inhibition of human telomerase reverse transcriptase by nonsteroidal antiinflammatory drugs in colon carcinoma[J]. Cancer,2006, 106: 1243-1249.
