期刊文献+

开角型青光眼相关基因的研究 被引量:9

Relevant gene study of primary open-angle glaucoma
暂未订购
导出
摘要 近年来国外在开角型青光眼遗传学方面的研究已取得显著进展,已确定了许多染色体位点与开角型青光眼发病有关,并且进行了相关基因的定位与克隆,以及其突变位点的分析,本文就开角型青光眼相关基因的研究进行综述。 Recently, the research of primary open-angle glaucoma (POAG) genetics has made great progress from abroad. Many chromosome locations hava been confirmed, and related genes were located and cloned, in addition, the mutation of related genes was analyzed. This paper reviews relevant gene study of POAG.
出处 《国际眼科杂志》 CAS 2005年第4期711-714,共4页 International Eye Science
关键词 开角型青光眼相关基因 遗传学 染色体位点 基因克隆 病理机制 primary open-angle glaucoma heredity gene
  • 相关文献

参考文献29

  • 1Polansky JR,Fauss DJ,Chen P,Chen H,Lutjen-Drecoll E,Johnson D,Kurtz RM,Ma ZD,Bloom E,Nguyen TD.Cellular pharmacology and molecular biology of the trabecular meshwork inducible glucocorticoid response gene product.Ophthalmologica,1997;211(3):126-139.
  • 2Cobb C J,Scott G,Swingler R J,Wilson S,Ellis J,MacEwen C J,McLean WH.Rapid mutation detection by the transgenomic wave analyser DHPLC identifies MYOC mutations in patients with ocular hypertension and/or open angle glaucoma.Br J Ophthalmol,2002;86(2):191-195.
  • 3Challa P,Herndon LW,Hauser MA,Broomer BW,Pericak-Vance MA,Ababio-Danso B,Allingham RR.Prevalence of myocilin mutations in adults with primary open-angle glaucoma in Ghana,west Africa.J Glaucoma,2002;11(5):416-420.
  • 4Alward WL,Kwon YH,Khanna CL,Johnson AT,Hayreh SS,Zimmerman MB,Narkiewicz J,Andoff JL,Moore PA,Fingert JH,Sheffield VC,Stone EM.Variations in the myocilin gene in patients with open-angle glaucoma.Arch Ophthalmol,2002;120:1189-1197.
  • 5Sheffield VC,Stone EM,Alward WL,Drack AV,Johnson AT,Streb LM,Nichols BE.Genetic linkage of family open angle glaucoma to chromosome 1q21-31 .Nat Genet,1993;4:47-50.
  • 6Takahashi H,Noda S,Imamura Y,Nagasawa A,Kubota R,Mashima Y,Kudoh J,Oguchi Y,Shimizu N.Mouse myocilin(Myoc)gene expression in ocular tissues.Biochem Biophys Res Commun,1998;248(1):104-109.
  • 7Ueda J,Wentz-Hunter KK,Cheng EL,Fukuchi T,Abe H,Yue BY.Ultrastructural localization of myocilin in human trabecular meshwork cells and tissues.J Histochem Cytochem ,2000;48(10):1321 1330.
  • 8Tawara A,Okada Y,Kubota T,Suzuki Y,Taniguchi F,Shirato S,Nguyen TD,Ohnishi Y.Immunohistochemical localization of MYOC/TIGR protein in the trabecular tissue of normal and glaucomatous eyes.Curr EyeRes ,2000;21(6):934-943.
  • 9Russell P,Tamm ER,Grehn FJ,Picht G,Johnson M.The presence and properties of myocilin in the aqueous humor.Invest Ophthalmol Vis Sci,2001;42(5):983-986.
  • 10Kubota R,Noda S,Wang Y,Minoshima S,Asakawa S,Kudoh J,Mashima Y,Oguchi Y,Shimizu N.A novel myosin-like protein(myocilin)expressed in the connecting cilium of the photoreceptor molecular cloning,tissue expression,and chromosomal mapping.Genomics,1997;41:360-369.

同被引文献108

引证文献9

二级引证文献53

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部