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吡喹酮、阿苯达唑剂量递增疗法治疗脑囊虫病415例疗效观察 被引量:21

OBSERVATION ON TREATMENT OF 415 NEUROCYSTICERCOSIS CASES WITH PRAZIQ UANTEL AND ALBENDAZOLE ADMINISTERED ON INCREASING -DOSE REGIME
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摘要 应用吡喹酮(PQT)、阿苯达唑(ALB)3种疗法治疗脑囊虫病415例:1.PQT30mg/kg·d×12,第2、3疗程为30~50mg/kg·d×12,疗程间隔2~3个月。2.PQT10mg/kg·d×12,递增至30~50mg/kg·d×12,疗程间隔2~3个月。3.ALB、PQT联合治疗,共3个疗程。总治愈率为88.43%,总有效率为99.76%。 Satisfactory results were obtained on 415 cases with neurocysticercosis treatedwith praziquantel and albendazole. The theraputics used were:(1) praziquantel 30 mg/kg·d×12 and repeating the same course or increasing the dosage to 50 mg/kg·d×12 after 2-3monthsinterval;(2) praziquantel 10 mg/kg·d×12 and gradually increasing to 30-50 mg/kg·d×12with the course intervalof 2-3months;(3) praziquantel combined with albendazole. The totaldoses either of both drugs for each case was similar. The cure rate was 88. 43%and effectivenessrate 99. 76%. The treatment for reducing intracranial hypertension and anti-epilepsy wasadministered as well according to the intensity of reaction occurred during the anticysticercuscourses.
出处 《中国寄生虫病防治杂志》 CSCD 1995年第2期124-126,共3页 Chinese Journal of Parasitic Disease Control
关键词 脑囊虫病 吡喹酮 阿苯达唑 治疗 neurocysticercosis albendazole praziquantel
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